Title: Mixed oligonucleotide analogs with an acyclic carbohydrate moiety and a N-cyanoguanidine functionality
Authors: Pannecouque, Christophe
Schepers, Guy
Rozenski, Jef
Van Aerschot, Arthur
Claes, Paul
Herdewijn, Piet # ×
Issue Date: 1994
Publisher: Pergamon-elsevier science ltd
Series Title: Bioorganic & medicinal chemistry letters vol:4 issue:10 pages:1203-1206
Abstract: Mixed oligonucleotide analogues having a backbone structure with a N-cyanoguanidine functionality and an acyclic sugar moiety were synthesized This combination, however, has a detrimental effect on duplex stability of DNA-DNA hybrids.
ISSN: 0960-894X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
Formal and Computational Linguistics (ComForT), Leuven
Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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