The effect of modified quarter laser-assisted zona thinning on the implantation rate per embryo in frozen/vitrified-thawed/warmed embryo transfer cycles: a prospective randomized controlled trial

Debrock, Sophie; Peeraer, Karen; Spiessens, Carl; Willemen, Dirk; De Loecker, P; D'Hooghe, TM

doi:10.1093/humrep/der161

The effect of modified quarter laser-assisted zona thinning on the implantation rate per embryo in frozen/vitrified-thawed/warmed embryo transfer cycles: a prospective randomized controlled trial

Author:

Debrock, Sophie

Peeraer, Karen ; Spiessens, Carl ; Willemen, Dirk ; De Loecker, P ; D'Hooghe, TM

Keywords:

laser-assisted zona thinning, prospective randomized controlled trial, frozen-thawed embryo transfer cycles, implantation rate, cryopreserved-thawed embryos, pregnancy, benefit, Science & Technology, Life Sciences & Biomedicine, Obstetrics & Gynecology, Reproductive Biology, Adult, Cryopreservation, Embryo Implantation, Embryo Transfer, Embryo, Mammalian, Female, Humans, Lasers, Pregnancy, Vitrification, Zona Pellucida, 11 Medical and Health Sciences, 16 Studies in Human Society, Obstetrics & Reproductive Medicine, 3215 Reproductive medicine

Abstract:

BACKGROUND: Freezing/vitrifying and thawing/warming of embryos may impair the successful hatching process of the embryo out of its zona pellucida (ZP) and its following implantation into the uterus. Theoretically, assisted hatching (AH) may facilitate the hatching process and subsequently increase implantation rates (IRs).