Human Reproduction
Author:
Keywords:
laser-assisted zona thinning, prospective randomized controlled trial, frozen-thawed embryo transfer cycles, implantation rate, cryopreserved-thawed embryos, pregnancy, benefit, Science & Technology, Life Sciences & Biomedicine, Obstetrics & Gynecology, Reproductive Biology, Adult, Cryopreservation, Embryo Implantation, Embryo Transfer, Embryo, Mammalian, Female, Humans, Lasers, Pregnancy, Vitrification, Zona Pellucida, 11 Medical and Health Sciences, 16 Studies in Human Society, Obstetrics & Reproductive Medicine, 3215 Reproductive medicine
Abstract:
BACKGROUND: Freezing/vitrifying and thawing/warming of embryos may impair the successful hatching process of the embryo out of its zona pellucida (ZP) and its following implantation into the uterus. Theoretically, assisted hatching (AH) may facilitate the hatching process and subsequently increase implantation rates (IRs).