Title: Paradoxical Interictal Cerebral Cortical Hypermetabolism on Brain FDG PET in Sturge-Weber Syndrome
Authors: Al-Makhzomi, Mohamad ×
Goffin, Karolien
De Waele, Liesbeth
Lagae, Lieven
Van Laere, Koen #
Issue Date: Apr-2011
Publisher: Lippincott
Series Title: Clinical Nuclear Medicine vol:36 issue:4 pages:313-314
Abstract: Sturge-Weber syndrome (SWS) is a congenital, noninherited neurocutaneous syndrome, characterized by angiomas located in the facial skin and leptomeninges and often associated with severe epilepsy. We report a paradoxical finding on FDG PET with interictally increased metabolism in the affected hemisphere and contralateral cerebellum in an infant with epilepsy due to SWS. PET imaging was performed to assess the extent and degree of cerebral metabolic impairment before epilepsy surgery. Although the exact mechanism underlying this paradoxical hypermetabolism remains unclear, it may play an important role in the pathophysiologic progression of SWS.
ISSN: 0363-9762
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Nuclear Medicine & Molecular Imaging
Development and Regeneration, Campus Kulak Kortrijk
Department of Development and Regeneration - miscellaneous (+)
Organ Systems (+)
× corresponding author
# (joint) last author

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