Cancer Genetics and Cytogenetics
Author:
Keywords:
Adult, Child, Chromosome Aberrations, Chromosomes, Human, Pair 11, Chromosomes, Human, Pair 2, Chromosomes, Human, Pair 6, Female, Fibrous Dysplasia of Bone, Humans, Karyotyping, Science & Technology, Life Sciences & Biomedicine, Oncology, Genetics & Heredity, TUMORS, 1112 Oncology and Carcinogenesis, Oncology & Carcinogenesis, 3105 Genetics, 3211 Oncology and carcinogenesis
Abstract:
We report the cytogenetic findings of two cases of fibrous dysplasia, one occurring in the tibia, the other in the sphenoid. Both cases exhibited only one chromosome change: a t(6;11)(q15;p15) in the first case, a derivative chromosome 2 in the second. The previous cytogenetic report on fibrous dysplasia revealed only numerical changes. The significance of these inconsistent chromosomal findings in fibrous dysplasia is unclear.