Author:

Keywords:

Science & Technology, Physical Sciences, Chemistry, Organic, Chemistry, 1,2-epoxides, Lewis catalysts, Bronsted catalysts, solvent-free conditions, ALPHA,BETA-EPOXYCARBOXYLIC ACIDS, MICROWAVE IRRADIATION, ORGANIC SYNTHESES, EFFICIENT, WATER, EPOXIDES, RING, IODINATION, ALCOHOLS, 0304 Medicinal and Biomolecular Chemistry, 0305 Organic Chemistry, Organic Chemistry, 3101 Biochemistry and cell biology, 3404 Medicinal and biomolecular chemistry, 3405 Organic chemistry

Abstract:

Thiolysis of alkyl- and aryl-1,2-epoxides was investigated under solvent-free conditions in the presence of Lewis and Brønsted acid and base catalysts (InCl3, p-TsOH, n-Bu3P, K2CO3). Five mol% of catalyst was sufficient and the best results were obtained by using InCl3 and K2CO3. β-Hydroxy sulfide was isolated in excellent yields. © 2003 Elsevier Ltd. All rights reserved.