Ghrelin

Müller, TD; Nogueiras, R; Andermann, ML; Andrews, ZB; Anker, SD; Argente, J; Batterham, RL; Benoit, SC; Bowers, CY; Broglio, F; Casanueva, FF; D'Alessio, D; Depoortere, Inge; Geliebter, A; Ghigo, E; Cole, PA; Cowley, M; Cummings, DE; Dagher, A; Diano, S; Dickson, SL; Diéguez, C; Granata, R; Grill, HJ; Grove, K; Habegger, KM; Heppner, K; Heiman, ML; Holsen, L; Holst, B; Inui, A; Jansson, JO; Kirchner, H; Korbonits, M; Laferrère, B; LeRoux, CW; Lopez, M; Morin, S; Nakazato, M; Nass, R; Perez-Tilve, D; Pfluger, PT; Schwartz, TW; Seeley, RJ; Sleeman, M; Sun, Y; Sussel, L; Tong, J; Thorner, MO; van der Lely, AJ; van der Ploeg, LHT; Zigman, JM; Kojima, M; Kangawa, K; Smith, RG; Horvath, T; Tschöp, MH

doi:10.1016/j.molmet.2015.03.005

Ghrelin

Author:

Müller, TD

Nogueiras, R ; Andermann, ML ; Andrews, ZB ; Anker, SD ; Argente, J ; Batterham, RL ; Benoit, SC ; Bowers, CY ; Broglio, F ; Casanueva, FF ; D'Alessio, D ; Depoortere, Inge ; Geliebter, A ; Ghigo, E ; Cole, PA ; Cowley, M ; Cummings, DE ; Dagher, A ; Diano, S ; Dickson, SL ; Diéguez, C ; Granata, R ; Grill, HJ ; Grove, K ; Habegger, KM ; Heppner, K ; Heiman, ML ; Holsen, L ; Holst, B ; Inui, A ; Jansson, JO ; Kirchner, H ; Korbonits, M ; Laferrère, B ; LeRoux, CW ; Lopez, M ; Morin, S ; Nakazato, M ; Nass, R ; Perez-Tilve, D ; Pfluger, PT ; Schwartz, TW ; Seeley, RJ ; Sleeman, M ; Sun, Y ; Sussel, L ; Tong, J ; Thorner, MO ; van der Lely, AJ ; van der Ploeg, LHT ; Zigman, JM ; Kojima, M ; Kangawa, K ; Smith, RG ; Horvath, T ; Tschöp, MH

Keywords:

Science & Technology, Life Sciences & Biomedicine, Endocrinology & Metabolism, Ghrelin, Growth hormone segretagogue receptor, GROWTH-HORMONE SECRETAGOGUE, DES-ACYL GHRELIN, O-ACYLTRANSFERASE GOAT, HIGH-FAT-DIET, BROWN ADIPOSE-TISSUE, BODY-MASS INDEX, LAPAROSCOPIC SLEEVE GASTRECTOMY, STIMULATES LOCOMOTOR-ACTIVITY, BETA-ADRENERGIC-RECEPTORS, INCREASES FOOD-INTAKE, 0601 Biochemistry and Cell Biology, 0606 Physiology, 3101 Biochemistry and cell biology

Abstract:

The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the hormone, which go beyond the regulation of systemic energy metabolism.