Author:

Keywords:

Tissue Doppler imaging, Fetal echocardiography, Repeatability, Science & Technology, Life Sciences & Biomedicine, Obstetrics & Gynecology, FETAL CARDIAC-FUNCTION, ECHOCARDIOGRAPHY, GESTATION, REPRODUCIBILITY, REPEATABILITY, RELIABILITY, INDEXES, CHARTS, HEART, Adult, Echocardiography, Doppler, Female, Fetus, Heart, Humans, Pregnancy, Reference Values, Reproducibility of Results, Ultrasonography, Prenatal, 1114 Paediatrics and Reproductive Medicine, Obstetrics & Reproductive Medicine, 3213 Paediatrics, 3215 Reproductive medicine

Abstract:

INTRODUCTION: Recent studies have reported variations of up to 30% between different ultrasound machines for tissue Doppler imaging (TDI), a problem that can significantly impact clinical diagnosis, patient management and research studies. The objective of this study was to assess repeatability and agreement between fetal myocardial peak velocities evaluated by TDI with two different ultrasound systems. MATERIALS AND METHODS: Systolic (S'), early (E') and late (A') diastolic myocardial peak velocities at mitral and tricuspid annuli as well as at the basal septum were evaluated by spectral TDI in 150 fetuses using two different ultrasound systems: Siemens Antares (Siemens Medical Systems, Malvern, Pa., USA) and Vivid Q (General Electric Healthcare, Horten, Norway). A method comparison study was performed, calculating intraclass correlation coefficients (ICC), and agreement was assessed by Bland-Altman plots. RESULTS: Annular peak velocities showed lower values when measured by Vivid Q compared to values measured by Siemens Antares. ICC ranged from 0.07 (septal S') to 0.33 (right A'), showing very poor repeatability for clinical application. Agreement between the two systems was also poor, with high coefficients of variation for all measurements. CONCLUSIONS: Fetal annular peak velocities obtained with different ultrasound systems are not directly comparable. This is consistent with previous data in adults and warrants the need of system-specific reference values, suggesting that the same ultrasound machine should be used for longitudinal follow-up.