American Heart Journal
Author:
Keywords:
Science & Technology, Life Sciences & Biomedicine, Cardiac & Cardiovascular Systems, Cardiovascular System & Cardiology, NATRIURETIC PEPTIDE, TREPROSTINIL, PROSTACYCLIN, SODIUM, Adult, Aged, Antihypertensive Agents, Cardiac Catheterization, Dose-Response Relationship, Drug, Epoprostenol, Exercise Tolerance, Familial Primary Pulmonary Hypertension, Female, Follow-Up Studies, Hemodynamics, Humans, Hypertension, Pulmonary, Infusions, Intravenous, Male, Middle Aged, Patient Satisfaction, Prospective Studies, Single-Blind Method, Surveys and Questionnaires, Treatment Outcome, Young Adult, 1102 Cardiorespiratory Medicine and Haematology, 1117 Public Health and Health Services, Cardiovascular System & Hematology, 3201 Cardiovascular medicine and haematology
Abstract:
Continuous infusion of epoprostenol is the treatment of choice in patients with pulmonary arterial hypertension in functional classes III to IV. However, this treatment's limitations include instability at room temperature. A new epoprostenol formulation offers improved storage conditions and patient convenience.