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Clinical Pharmacokinetics

Publication date: 2017-02-01
Volume: 56 Pages: 193 - 205
Publisher: ADIS Press International

Author:

Delanaye, Pierre
Guerber, Fabrice ; Scheen, André ; Ellam, Timothy ; Bouquegneau, Antoine ; Guergour, Dorra ; Mariat, Christophe ; Pottel, Hans

Keywords:

Science & Technology, Life Sciences & Biomedicine, Pharmacology & Pharmacy, GLOMERULAR-FILTRATION-RATE, ELDERLY HOSPITALIZED-PATIENTS, CREATININE-BASED EQUATIONS, SERUM CYSTATIN C, RENAL-DISEASE, DOSING RECOMMENDATIONS, DOSE ADJUSTMENT, CANCER-PATIENTS, DIET, GFR, Adult, Aged, Aged, 80 and over, Cohort Studies, Dose-Response Relationship, Drug, Female, Glomerular Filtration Rate, Humans, Male, Middle Aged, Models, Biological, Pharmaceutical Preparations, Renal Insufficiency, Chronic, Young Adult, 1115 Pharmacology and Pharmaceutical Sciences, 3214 Pharmacology and pharmaceutical sciences

Abstract:

The dosages of many medications require adjustment for renal function. There is debate regarding which equation, the Chronic Kidney Disease Epidemiology (CKD-EPI) equation vs. the Cockcroft-Gault (CG) equation, should be recommended to estimate glomerular filtration rate.