Magnetic Resonance Materials in Biology, Physics and Medicine
Author:
Keywords:
Animals, Corpus Striatum, Disease Models, Animal, Female, Magnetic Resonance Imaging, Oxidopamine, Parkinsonian Disorders, Positron-Emission Tomography, Rats, Rats, Wistar, Reproducibility of Results, Sensitivity and Specificity, Science & Technology, Life Sciences & Biomedicine, Radiology, Nuclear Medicine & Medical Imaging, Parkinson's disease, Rat, Neurodegeneration, SPECT, MRI, DOPAMINE TRANSPORTER, MAGNETIC-RESONANCE, IRON CONTENT, CAUDATE-PUTAMEN, ALPHA-SYNUCLEIN, PINHOLE SPECT, IN-VIVO, BRAIN, NEURONS, OVEREXPRESSION, Radiography, Nuclear Medicine & Medical Imaging
Abstract:
In the present study, we aimed to evaluate the impact of neurodegeneration of the nigrostriatal tract in a rodent model of Parkinson's disease on the different MR contrasts (T(2), T(1), CBF and CBV) measured in the striatum.