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AMPK-mediated modulation of lipid droplets shapes melanoma cell vulnerability to ferroptosis

Publication date: 2024-12-20

Author:

Motamedi, Sahar
Swinnen, Johannes

Abstract:

In this project we aim to explore the concept of modulating the cancer cell's lipid composition as an approach to sensitize advanced and therapy-resistant cancer to lipid-based cell death therapies and to overcome therapy resistance.