Prdm16 Supports Arterial Flow Recovery by Maintaining Endothelial Function

Craps, Sander; Van Wauwe, Jore; De Moudt, Sofie; De Munck, Dorien; Leloup, Arthur JA; Boeckx, Bram; Vervliet, Tim; Dheedene, Wouter; Criem, Nathan; Geeroms, Carla; Jones, Elizabeth A; Zwijsen, An; Lambrechts, Diether; Fransen, Paul; Beerens, Manu; Luttun, Aernout

doi:10.1161/CIRCRESAHA.120.318501

Prdm16 Supports Arterial Flow Recovery by Maintaining Endothelial Function

Author:

Craps, Sander

Van Wauwe, Jore ; De Moudt, Sofie ; De Munck, Dorien ; Leloup, Arthur JA ; Boeckx, Bram ; Vervliet, Tim ; Dheedene, Wouter ; Criem, Nathan ; Geeroms, Carla ; Jones, Elizabeth A ; Zwijsen, An ; Lambrechts, Diether ; Fransen, Paul ; Beerens, Manu ; Luttun, Aernout

Keywords:

Science & Technology, Life Sciences & Biomedicine, Cardiac & Cardiovascular Systems, Hematology, Peripheral Vascular Disease, Cardiovascular System & Cardiology, arteries, endothelium, homeostasis, ischemia, transcription factor, vasodilation, THERAPEUTIC ANGIOGENESIS, RISK-FACTORS, COMMUNICATION, HETEROGENEITY, MITOCHONDRIA, DYSFUNCTION, PERFUSION, DELETION, GENE, Animals, Aorta, Calcium, Calcium Signaling, Cells, Cultured, Collateral Circulation, DNA-Binding Proteins, Disease Models, Animal, Endothelial Cells, Endothelium, Vascular, Femoral Artery, Hindlimb, Ischemia, Male, Mice, Inbred C57BL, Mice, Knockout, Muscle, Smooth, Vascular, Myocytes, Smooth Muscle, Neovascularization, Physiologic, Regional Blood Flow, Transcription Factors, Mice, Ca2+ homeostasis, Prdm16, endothelial dysfunction, nitric oxide bioavailability, C14/19/095#55221737, 12ZG121N#55744113, G099521N#56127218, KA/20/063#56130151, 1102 Cardiorespiratory Medicine and Haematology, 1103 Clinical Sciences, Cardiovascular System & Hematology, 3201 Cardiovascular medicine and haematology, 3202 Clinical sciences

Abstract:

[Figure: see text].