Author:

Keywords:

Science & Technology, Physical Sciences, Chemistry, Organic, Chemistry, CYSTEINE PROTEASE INHIBITOR, VINYL SULFONES, DECARBOXYLATIVE SULFONYLATION, STEREOSELECTIVE-SYNTHESIS, CINNAMIC-ACIDS, SULFUR-DIOXIDE, EOSIN Y, C-S, LIGHT, ARYL, 0304 Medicinal and Biomolecular Chemistry, 0305 Organic Chemistry, Organic Chemistry, 3404 Medicinal and biomolecular chemistry, 3405 Organic chemistry

Abstract:

(Het)Arylallenes undergo hydrosulfonylation under photoredox-catalyzed conditions. The reaction gives vinyl sulfones in a regio- and diastereoselective manner, employing sodium sulfinates as the sulfonyl source and eosin Y as the photocatalyst. Indol-1-yl, pyrrol-1-yl, phenyl, and naphtylallenes might be used. Aliphatic allenes are incompatible with the reaction conditions.