Natural nitration of CXCL12 at tyrosine 7 reduces its in vitro signaling and chemotactic activity and abrogates in vivo lymphocyte migration to intra-articularly injected CXCL12 in mice treated with the CD26 inhibitor sitagliptin

Janssens, Rik; Mortier, Anneleen; Boff, Daiane; Vanheule, Vincent; Struyf, Sofie; Van Damme, Jo; Amaral, Flavio Almeida; Teixeira, Mauro Martins; Proost, Paul

Natural nitration of CXCL12 at tyrosine 7 reduces its in vitro signaling and chemotactic activity and abrogates in vivo lymphocyte migration to intra-articularly injected CXCL12 in mice treated with the CD26 inhibitor sitagliptin

Author:

Janssens, Rik

Mortier, Anneleen ; Boff, Daiane ; Vanheule, Vincent ; Struyf, Sofie ; Van Damme, Jo ; Amaral, Flavio Almeida ; Teixeira, Mauro Martins ; Proost, Paul