Author:

Keywords:

Science & Technology, Life Sciences & Biomedicine, Urology & Nephrology, Galanin, Erectile Dysfunction, Radical Prostatectomy, Neuroregeneration, Nerve Culture, Cavernous Nerve Injury, MAJOR PELVIC GANGLION, RADICAL PROSTATECTOMY, NEURITE OUTGROWTH, SENSORY NEURONS, SPINAL-CORD, EXPRESSION, IMMUNOSYMPATHECTOMY, RECEPTORS, AXOTOMY, Animals, Disease Models, Animal, Male, Nerve Growth Factors, Nerve Regeneration, Nitrergic Neurons, Penile Erection, Penis, Peripheral Nerve Injuries, Prostatectomy, Rats, Rats, Sprague-Dawley, Receptors, Galanin, Recovery of Function, 11 Medical and Health Sciences, 17 Psychology and Cognitive Sciences, Obstetrics & Reproductive Medicine, 32 Biomedical and clinical sciences, 42 Health sciences, 52 Psychology

Abstract:

Previously, we found that the neuropeptide galanin was strongly upregulated soon after bilateral cavernous nerve injury (BCNI) and that galanin and its receptors were expressed in nitrergic erectile innervation. Galanin has been observed to exert neuroregenerative effects in dorsal root ganglion neurons, but evidence for these effects in the major pelvic ganglion (MPG) after BCNI is lacking.