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EFSA Journal

Publication date: 2018-01-01
Volume: 16
Publisher: Wiley

Author:

Younes, Maged
Aggett, Peter ; Aguilar, Fernando ; Crebelli, Riccardo ; Dusemund, Birgit ; Filipic, Metka ; Frutos, Maria Jose ; Galtier, Pierre ; Gundert-Remy, Ursula ; Kuhnle, Gunter Georg ; Lambre, Claude ; Leblanc, Jean-Charles ; Lillegaard, Inger Therese ; Moldeus, Peter ; Mortensen, Alicja ; Oskarsson, Agneta ; Stankovic, Ivan ; Waalkens-Berendsen, Ine ; Woutersen, Rudolf Antonius ; Wright, Matthew ; Herman, Lieve ; Tobback, Paul ; Pizzo, Fabiola ; Smeraldi, Camilla ; Tard, Alexandra ; Papaioannou, Adamantia ; Gott, David

Keywords:

Science & Technology, Life Sciences & Biomedicine, Food Science & Technology, food additive, low-substituted hydroxypropyl cellulose, L-HPC, food supplements, CHROMATOGRAPHY, L‐HPC, low‐substituted hydroxypropyl cellulose, EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS)

Abstract:

Low-substituted hydroxypropyl cellulose (L-HPC) is a low-substituted poly(hydroxypropyl) ether of cellulose. L-HPC is proposed for use as a food additive in food supplements in solid form (tablet), with a maximum use level of 20,000 mg/kg and a typical use level of 10,000 mg/kg. Exposure estimates to L-HPC from its proposed use were calculated for both typical and maximum use levels. Due to the close chemical relationship between L-HPC and other celluloses recently re-evaluated by EFSA, the Panel decided to read-across the biological data already evaluated in the context of the re-evaluation programme. The Panel concluded that there was no safety concern from the proposed use and use levels of L-HPC.