Of Mice and Women: a Laparoscopic Mouse Model for Endometriosis

Peterse, Daniëlle; Binda, Mercedes; O, Dorien; Vanhie, Arne; Fassbender, Amelie; Vriens, Joris; D'Hooghe, Thomas

doi:10.1016/j.jmig.2017.10.008

Of Mice and Women: a Laparoscopic Mouse Model for Endometriosis

Author:

Peterse, Daniëlle

Binda, Mercedes ; O, Dorien ; Vanhie, Arne ; Fassbender, Amelie ; Vriens, Joris ; D'Hooghe, Thomas

Keywords:

Science & Technology, Life Sciences & Biomedicine, Obstetrics & Gynecology, Decidualization, Estrogen, Endometrium, Menstruation, Progesterone, Animals, Disease Models, Animal, Endometriosis, Estrogens, Female, Humans, Laparoscopy, Menstrual Cycle, Mice, Inbred C57BL, Progestins, 1114 Paediatrics and Reproductive Medicine, Obstetrics & Reproductive Medicine, 3215 Reproductive medicine

Abstract:

To demonstrate how a novel laparoscopic approach allows the development of a mouse model for endometriosis after seeding menstrual endometrium from donor mice into the abdominal cavity of syngeneic recipient mice.