Author:

Keywords:

Social Sciences, Science & Technology, Life Sciences & Biomedicine, Psychology, Clinical, Public, Environmental & Occupational Health, Social Sciences, Interdisciplinary, Social Sciences, Biomedical, Psychology, Social Sciences - Other Topics, Biomedical Social Sciences, Trans woman, meningioma, estrogen, progesterone, cyproterone acetate, SEX HORMONE-TREATMENT, TRANSSEXUAL PATIENT, ESTROGEN, THERAPY, RISK, 1699 Other Studies in Human Society, 1701 Psychology, Public Health, 4206 Public health, 4405 Gender studies, 5205 Social and personality psychology

Abstract:

© 2018 Taylor & Francis Group, LLC. Background: Meningiomas express estrogen and progesterone receptors, suggestive of hormonal responsiveness. So far, eight cases of trans women with a meningioma have been reported in the literature. Methods: Detailed report of the symptoms, treatment, and follow-up of an individual transgender patient with a meningioma. Results: A trans woman treated long-term with gender affirming hormone therapy, including cyproterone acetate, a synthetic progestin and anti-androgen, was diagnosed with a meningioma, significantly expanding in volume over 10 years. After stopping cyproterone acetate a substantial volume decrease of the meningioma was noticed within 3 months. Conclusion: This addition to the literature demonstrates that a conservative approach with interruption of cyproterone acetate may be a sufficient intervention, obviating the need for additional neurosurgical treatment.