Regional variation in quality of life in patients with a Fontan circulation: A multinational perspective

Fogleman, Nicholas D; Apers, Silke; Moons, Philip; Morrison, Stacey; Wittekind, Samuel G; Tomlin, Martha; Gosney, Kathy; Sluman, Maayke A; Johansson, Bengt; Enomoto, Junko; Dellborg, Mikael; Lu, Chun-Wei; Subramanyan, Raghavan; Luyckx, Koen; Budts, Werner; Jackson, Jamie; Kovacs, Adrienne; Soufi, Alexandra; Eriksen, Katrine; Thomet, Corina; Berghammer, Malin; Callus, Edward; Fernandes, Susan M; Caruana, Maryanne; Cook, Stephen C; Mackie, Andrew S; White, Kamila S; Khairy, Paul; Kutty, Shelby; Veldtman, Gruschen

doi:10.1016/j.ahj.2017.07.019

Regional variation in quality of life in patients with a Fontan circulation: A multinational perspective

Author:

Fogleman, Nicholas D

Apers, Silke ; Moons, Philip ; Morrison, Stacey ; Wittekind, Samuel G ; Tomlin, Martha ; Gosney, Kathy ; Sluman, Maayke A ; Johansson, Bengt ; Enomoto, Junko ; Dellborg, Mikael ; Lu, Chun-Wei ; Subramanyan, Raghavan ; Luyckx, Koen ; Budts, Werner ; Jackson, Jamie ; Kovacs, Adrienne ; Soufi, Alexandra ; Eriksen, Katrine ; Thomet, Corina ; Berghammer, Malin ; Callus, Edward ; Fernandes, Susan M ; Caruana, Maryanne ; Cook, Stephen C ; Mackie, Andrew S ; White, Kamila S ; Khairy, Paul ; Kutty, Shelby ; Veldtman, Gruschen

Keywords:

Science & Technology, Life Sciences & Biomedicine, Cardiac & Cardiovascular Systems, Cardiovascular System & Cardiology, CONGENITAL HEART-DISEASE, REPORTED OUTCOMES, HEALTH-STATUS, ADULTS, ADOLESCENTS, COMPLICATIONS, EXPERIENCES, PATTERNS, CHILDREN, SINGLE, Adult, Anxiety Disorders, Cross-Sectional Studies, Female, Follow-Up Studies, Global Health, Heart Septal Defects, Atrial, Heart Septal Defects, Ventricular, Humans, Incidence, Male, Prevalence, Quality of Life, APPROACH-IS consortium, 1102 Cardiorespiratory Medicine and Haematology, 1117 Public Health and Health Services, Cardiovascular System & Hematology, 3201 Cardiovascular medicine and haematology

Abstract:

Impaired quality of life (QOL) is associated with congenital heart disease (CHD) and country of residence; however, few studies have compared QOL in patients with differing complexities of CHD across regional populations. The current study examined regional variation in QOL outcomes in a large multinational sample of patients with a Fontan relative to patients with atrial septal defects (ASDs) and ventricular septal defects (VSDs).