Longitudinal qPCR study of the dynamics of L. crispatus, L. iners, A. vaginae, (sialidase positive) G. vaginalis, and P. bivia in the vagina

Santiago, Guido Lopes dos Santos; Tency, Inge; Verstraelen, Hans; Verhelst, Rita; Trog, Marijke; Temmerman, Marleen; Vancoillie, Leen; Decat, Ellen; Cools, Piet; Vaneechoutte, Mario

doi:10.1371/journal.pone.0045281

Longitudinal qPCR study of the dynamics of L. crispatus, L. iners, A. vaginae, (sialidase positive) G. vaginalis, and P. bivia in the vagina

Author:

Santiago, Guido Lopes dos Santos

Tency, Inge ; Verstraelen, Hans ; Verhelst, Rita ; Trog, Marijke ; Temmerman, Marleen ; Vancoillie, Leen ; Decat, Ellen ; Cools, Piet ; Vaneechoutte, Mario

Keywords:

Actinobacteria, Adolescent, Adult, Bacterial Load, Female, Gardnerella vaginalis, Gentian Violet, Humans, Hydrogen Peroxide, Lactobacillus, Longitudinal Studies, Menstrual Cycle, Menstruation, Microbial Consortia, Neuraminidase, Phenazines, Prevotella, Real-Time Polymerase Chain Reaction, Vagina, Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, PEROXIDE-PRODUCING LACTOBACILLI, FEMALE GENITAL-TRACT, BACTERIAL VAGINOSIS, HYDROGEN-PEROXIDE, GARDNERELLA-VAGINALIS, ATOPOBIUM-VAGINAE, PREGNANT-WOMEN, MENSTRUAL-CYCLE, GRAM STAIN, MICROFLORA, General Science & Technology

Abstract:

To obtain more detailed understanding of the causes of disturbance of the vaginal microflora (VMF), a longitudinal study was carried out for 17 women during two menstrual cycles.