Download PDF (external access)

Clinical science and molecular medicine. Supplement

Publication date: 1976-12-01
Pages: 215 -
Publisher: BIOCHEMICAL SOC

Author:

Fagard, Robert
Amery, A ; Deplaen, JF ; Lijnen, Paul ; Missotten, A

Keywords:

Antihypertensive Agents, Atenolol, Bendroflumethiazide, Clinical Trials, Humans, Hypertension, Propanolamines, Renin, Science & Technology, Life Sciences & Biomedicine, Biochemistry & Molecular Biology, Clinical Trials as Topic

Abstract:

1. The anti-hypertensive effect of atenolol was greater than that of bendrofluazide. 2. The change in systolic blood pressure caused by bendrofluazide showed a significant inverse correlation iwth the plasma renin concentration (r=-0-47; P less than 0-01). 3.The correlation between the change in systolic blood pressure caused by atenolol and the plasma renin concentration was not significant (r =0-28; 0-1 greater than P greater than 0-05). 4. Plasma renin concentration was unaffected by atenolol.