You are here: Lirias

Items for Author "Gysemans, Conny; U0024364"

Return to Browse by Author
Sort by Title Sorting by Date

Showing 146 items.

Date of IssueTitle Contributors
Feb-2015 Vitamin D3 Induces Tolerance in Human Dendritic Cells by Activation of Intracellular Metabolic PathwaysBomfim Ferreira, Gabriela; Vanherwegen, An-Sofie; Eelen, Guy; Gutiérrez, Ana Carolina Fierro; Van Lommel, Leentje; Marchal, Kathleen; Verlinden, Lieve; Verstuyf, Mieke; Nogueira, Tatiane Cristina; Georgiadou, Maria; Schuit, Frans; Eizirik, Décio L; Gysemans, Conny; Carmeliet, Peter; Overbergh, Lut; Mathieu, Chantal
Jan-2015 Macrophage dynamics are regulated by local macrophage proliferation and monocyte recruitment in injured pancreasVan Gassen, Naomi; Van Overmeire, Eva; Leuckx, Gunter; Heremans, Yves; De Groef, Sofie; Elkrim, Yvon; Gysemans, Conny; Stijlemans, Benoît; Van de Casteele, Mark; De Baetselier, Patrick; De Leu, Nico; Heimberg, Harry; Van Ginderachter, Jo A
Jan-2015 Trimming of two major type 1 diabetes driving antigens, GAD65 and IA-2, allows for successful expression in Lactococcus lactisRobert, Sofie; Van Huynegem, K; Gysemans, Conny; Mathieu, Chantal; Rottiers, P; Steidler, L
Aug-2014 Oral delivery of Glutamic Acid Decarboxylase (GAD)-65 and IL10 by Lactococcus lactis reverses diabetes in recent-onset NOD miceRobert, Sofie; Gysemans, Conny; Takiishi, Tatiana; Korf, Hannelie; Spagnuolo, Isabella; Sebastiani, Guido; Van Huynegem, Karolien; Steidler, Lothar; Caluwaerts, Silvia; Demetter, Pieter; Wasserfall, Clive H; Atkinson, Mark A; Dotta, Francesco; Rottiers, Pieter; Van Belle, Tom; Mathieu, Chantal
9-Jul-2014 ActoBioticsTM voor antigeen-specifieke interventie in type 1 diabetes: mono- of combinatietherapieRobert, Sofie; Mathieu, Chantal (supervisor); Gysemans, Conny (cosupervisor)
Jul-2014 Clinical Immunosuppressants Inhibit Inflammatory, Proliferative And Reprogramming Potential, But Not Angiogenesis Of Human Pancreatic Duct CellsDing, Lei; Heremans, Yves; Pipeleers, Daniel; Ling, Zhidong; Heimberg, Harry; Gysemans, Conny; Mathieu, Chantal
Jul-2014 A combined ″omics″ approach identifies NMI as a novel cytokine-induced regulator of IRE1α and JNK in pancreatic beta cellsBrozzi, Flora; Gerlo, Sarah; Grieco, Fabio Arturo; Nardelli, Tarlliza R; Lievens, Sam; Gysemans, Conny; Marselli, Lorella; Marchetti, Piero; Mathieu, Chantal; Tavernier, Jan; Eizirik, Decio L
27-Jun-2014 Therapies In Type 1 Diabetes: Studying The Interaction Between The Beta-Cell And The Immune System Using Preclinical ModelsDing, Lei; Mathieu, Chantal (supervisor); Overbergh, Lut (cosupervisor); Gysemans, Conny (cosupervisor)
Jun-2014 Dietary supplementation with high doses of regular vitamin D3 safely reduces diabetes incidence in nod mice when given early and long-termTakiishi, Tatiana; Ding, Lei; Baeke, Femke; Spagnuolo, Isabella; Sebastiani, Guido; Laureys, Jos; Verstuyf, Annemieke; Carmeliet, Geert; Dotta, Francesco; Van Belle, Tom; Gysemans, Conny; Mathieu, Chantal
May-2014 1,25-Dihydroxyvitamin D3 Promotes Tolerogenic Dendritic Cells with Functional Migratory Properties in NOD MiceBomfim Ferreira, Gabriela; Gysemans, Conny; Demengeot, Jocelyne; Monteiro Carvalho Mori Cunha, João Paulo; Vanherwegen, An-Sofie; Overbergh, Lut; Van Belle, Tom; Pauwels, Femke; Verstuyf, Annemieke; Korf, Hannelie; Mathieu, Chantal
27-Mar-2014 Oral delivery of Glutamic Acid Decarboxylase (GAD)-65 and IL10 by Lactococcus lactis reverses diabetes in recent-onset NOD miceRobert, Sofie; Gysemans, Conny; Takiishi, Tatiana; Korf, Hannelie; Van Belle, Tom; Mathieu, Chantal
Mar-2014 Islet infiltration, cytokine expression and beta cell death in the NOD mouse, BB rat, Komeda rat, LEW.1AR1-iddm rat and humans with type 1 diabetesJörns, Anne; Arndt, Tanja; Zu Vilsendorf, Andreas Meyer; Klempnauer, Jürgen; Wedekind, Dirk; Hedrich, Hans-Jürgen; Marselli, Lorella; Marchetti, Piero; Harada, Nagakatsu; Nakaya, Yutaka; Wang, Gen-Sheng; Scott, Fraser W; Gysemans, Conny; Mathieu, Chantal; Lenzen, Sigurd
Jan-2014 Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protectionChristensen, Dan Ploug; Gysemans, Conny; Lundh, Morten; Dahllöf, Mattias Salling; Noesgaard, Daniel; Schmidt, Søren Fisker; Mandrup, Susanne; Birkbak, Nikolai; Workman, Christopher T; Piemonti, Lorenzo; Blaabjerg, Lykke; Monzani, Valmen; Fossati, Gianluca; Mascagni, Paolo; Paraskevas, Steven; Aikin, Reid A; Billestrup, Nils; Grunnet, Lars Groth; Dinarello, Charles A; Mathieu, Chantal; ...
2014 The active enhancer network operated by liganded RXR supports angiogenic activity in macrophagesDaniel, Bence; Nagy, Gergely; Hah, Nasun; Horvath, Attila; Czimmerer, Zsolt; Poliska, Szilard; Gyuris, Tibor; Keirsse, Jiri; Gysemans, Conny; Van Ginderachter, Jo A; Balint, L. Balint; Evans, Ronald M; Barta, Endre; Nagy, Laszlo
2014 Antigen- Specific Therapy With Human Proinsulin and IL10 in Combination With Short- Course Monoclonal CD3 Antibody in Preclinical Models of Islet TransplantMonteiro Carvalho Mori Cunha, João Paulo; Takiishi, Tatiana; Van Belle, Tom; Korf, Hannelie; Rottiers, P; Steidler, L; Gysemans, Conny; Mathieu, Chantal
2014 A combined "omics" approach identifies NMI as a novel cytokine-induced regulator of IRE1 alpha and JNK in pancreatic beta cellsBrozzi, F; Gerlo, S; Grieco, F. A; Lievens, Sam; Gysemans, Conny; Marselli, L; Marchetti, P; Mathieu, Chantal; Tavernier, J; Eizirik, D. L
2014 1,25-Dihydroxyvitamin D-3 and Its Analog TX527 Promote a Stable Regulatory T Cell Phenotype in T Cells from Type 1 Diabetes PatientsVan Belle, Tom; An-Sofie Vanherwegen, An-Sofie; Feyaerts, Dorien; De Clercq, Pierre; Verstuyf, Annemieke; Korf, Hannelie; Gysemans, Conny; Mathieu, Chantal
2014 Combining MK626, a Novel DPP-4 Inhibitor, and Low-Dose Monoclonal CD3 Antibody for Stable Remission of New-Onset Diabetes in MiceDing, Lei; Gysemans, Conny; Stangé, Geert; Heremans, Yves; Yuchi, Yixing; Takiishi, Tatiana; Korf, Hannelie; Chintinne, Marie; Carr, Richard D; Heimberg, Harry; Pipeleers, Daniel; Mathieu, Chantal
2014 Antigen-Specific Therapy With Human Proinsulin and IL10 in Combination With Short-Course Monoclonal CD3 Antibody in Preclinical Models of Islet TransplantMonteiro Carvalho Mori Cunha, João Paulo; Takiishi, Tatiana; Van Belle, Tom; Korf, Hannelie; Rottiers, Pieter; Steidler, Lothar; Gysemans, Conny; Mathieu, Chantal
Nov-2013 Vitamin D and diabetes: the odd coupleVan Belle, Tom; Gysemans, Conny; Mathieu, Chantal
16-Sep-2013 NOVEL IMMUNOTHERAPIES IN TYPE 1 DIABETES: EXPLORING ANTIGEN-SPECIFIC AND NON-SPECIFIC APPROACHESTakiishi, Tatiana; Mathieu, Chantal (supervisor); Gysemans, Conny (cosupervisor)
Sep-2013 beta-Cell differentiation and regeneration in type 1 diabetesDing, Lei; Gysemans, Conny; Mathieu, Chantal
May-2013 Reversal of Hyperglycemia by Insulin-Secreting Rat Bone Marrow- and Blastocyst-Derived Hypoblast Stem Cell-Like CellsKumar, Anujith; Lo Nigro, Antonio; Gysemans, Conny; Cai, Qing; Esguerra, Camila; Nelson-Holte, Molly; Heremans, Yves; Jimenez-Gonzalez, Maria; Porciuncula, Angelo; Mathieu, Chantal; Binas, Bert; Heimberg, Harry; Prosper, Felipe; Hering, Bernhard; Verfaillie, Catherine; Barajas, Miguel
Mar-2013 Effects of Vitamin D on Antigen-specific and Antigen-non-specific Immune Modulation: Relevance for Type 1 DiabetesTakiishi, Tatiana; Van Belle, Tom; Gysemans, Conny; Mathieu, Chantal
Jan-2013 Antigen-based vs. systemic immunomodulation in type 1 diabetes: the pros and consRobert, Sofie; Korf, Hannelie; Gysemans, Conny; Mathieu, Chantal
2013 1,25-dihydroxyvitamin D3 and its Analogue TX527 Promote a Regulatory T Cell Phenotype in T Cells from Type 1 Diabetic PatientsVan Belle, Tom; Feyaerts, Dorien; Declercq, Pierre; Verstuyf, Annemieke; Carmeliet, Geert; Gysemans, Conny; Mathieu, Chantal
2013 Oral delivery of Glutamic Acid Decarboxylase (GAD)-65 and IL10 by Lactococcus lactis reverses diabetes in recent-onset NOD miceRobert, Sofie; Gysemans, Conny; Takiishi, Tatiana; Korf, Hannelie; Van Belle, Tom; Mathieu, Chantal
2013 Restoration of normoglycemia in diabetic NOD mice by oral L.lactis secreting human pro-insulin plus IL-10 combined with short-term low-dose anti-CD3 is dependent on FOXP3+ TregsTakiishi, Tatiana; Van Belle, Tom; Robert, Sofie; Korf, Hannelie; Rottiers, Pieter; Gysemans, Conny; Mathieu, Chantal
2013 MK0626, a DPP-4 inhibitor for use in mice, in combination with low-dose systemic anti-CD3 stably reverses new-onset diabetes in non-obese diabetic miceDing, Lei; Takiishi, Tatiana; Korf, Hannelie; Gysemans, Conny; Mathieu, Chantal
2013 Oral administration of L. Lactis secreting hGAD65370-575 and hIL-10 can revert diabetes in recent-onset NOD mice when combined with low-dose anti-CD3Robert, Sofie; Takiishi, Tatiana; Van Huynegem, Karolien; Steidler, Lothar; Korf, Hannelie; Gysemans, Conny; Van Belle, Tom; Rottiers, Pieter; Mathieu, Chantal
2013 Oral delivery of Glutamic Acid Decarboxylase (GAD)-65 and IL10 by Lactococcus lactis reverses diabetes in recent-onset NOD miceRobert, Sofie; Gysemans, Conny; Takiishi, Tatiana; Korf, Hannelie; Spagnuolo, Isabella; Van Huynegem, Karolien; Steidler, Lothar; Caluwaerts, Silvia; Demetter, Pieter; Wasserfall, Clive; Atkinson, Marc; Dotta, Francesco; Rottiers, Pieter; Van Belle, Tom; Mathieu, Chantal
2013 1,25-dihydroxyvitamin D3 promotes tolerogenic murine dendritic cells presenting functional migratory properties in vivoBomfim Ferreira, Gabriela; Gysemans, Conny; Monteiro Carvalho Mori Cunha, João Paulo; Overbergh, Lut; Van Belle, Tom; Verstuyf, Annemieke; Korf, Hannelie; Mathieu, Chantal
2013 1,25-dihydroxyvitamin D3 and its Analogue TX527 Promote a Regulatory T Cell Phenotype in T Cells from Type 1 Diabetic PatientsVan Belle, Tom; Feyaert, Dorien; Declercq, Pierre; Verstuyf, Annemieke; Gysemans, Conny; Mathieu, Chantal
Dec-2012 1,25 dihydroxyvitamin D3 curtails the inflammatory- and T cell stimulatory capacity of macrophages through an IL-10-dependent mechanismKorf, Hannelie; Wenes, Mathias; Stijlemans, Benoit; Takiishi, Tatiana; Robert, Sofie; Miani, Michela; Eizirik, Decio; Gysemans, Conny; Mathieu, Chantal
Nov-2012 Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress-Mitochondrial Dialog Triggering Lipotoxic Rodent and Human β-Cell ApoptosisCunha, Daniel A; Igoillo-Esteve, Mariana; Gurzov, Esteban N; Germano, Carla M; Naamane, Najib; Marhfour, Ihsane; Fukaya, Makiko; Vanderwinden, Jean-Marie; Gysemans, Conny; Mathieu, Chantal; Marselli, Lorella; Marchetti, Piero; Harding, Heather P; Ron, David; Eizirik, Décio L; Cnop, Miriam
Oct-2012 Low doses of anti-CD3, ciclosporin A and the vitamin D analogue, TX527, synergise to delay recurrence of autoimmune diabetes in an islet-transplanted NOD mouse model of diabetesBaeke, Femke; Van Belle, Tom L; Takiishi, Tatiana; Ding, Lei; Korf, Hannelie; Laureys, Jos; Gysemans, Conny; Mathieu, Chantal
Sep-2012 Extraskeletal Effects of Vitamin DWolden-Kirk, Heidi; Gysemans, Conny; Verstuyf, Annemieke; Mathieu, Chantal
Jun-2012 Liraglutide is more potent in stably reverting overt autoimmune diabetes in NOD mice compared to exendin-4 when combined with αCD3 antibodyDing, Lei; Takiishi, Tatiana; Van Belle, Tom; Korf, Hannelie; Overbergh, Lut; Gysemans, Conny; Mathieu, Chantal
9-Apr-2012 Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in miceTakiishi, Tatiana; Korf, Hannelie; Van Belle, Tom; Robert, Sofie; Grieco, Fabio A; Caluwaerts, Silvia; Galleri, Letizia; Spagnuolo, Isabella; Steidler, Lothar; Van Huynegem, Karolien; Demetter, Pieter; Wasserfall, Clive; Atkinson, Mark A; Dotta, Francesco; Rottiers, Pieter; Gysemans, Conny; Mathieu, Chantal
Feb-2012 Vitamin d and diabetesTakiishi, Tatiana; Gysemans, Conny; Bouillon, Roger; Mathieu, Chantal
Jan-2012 Deletion of C/EBP homologous protein (Chop) in C57Bl/6 mice dissociates obesity from insulin resistanceMaris, Michael; Overbergh, Lut; Gysemans, Conny; Waget, A; Cardozo, A K; Verdrengh, Eefje; Cunha, J P M; Gotoh, T; Cnop, M; Eizirik, D L; Burcelin, R; Mathieu, Chantal
2012 Using Vitamin D (analogs) to expand Tregs in vitro for adoptive immunotherapy in Type 1 DiabetesVan Belle, Tom; Feyaerts, Dorien; Overbergh, Lut; Gysemans, Conny; Mathieu, Chantal
2012 Deletion of C/EBP homologous protein Chop induces abdominal obesity and dissociates obesity from insulin resistance by suppression of inflammationMaris, Michael; Overbergh, Lut; Gysemans, Conny; Waget, Aurelie; Orntoft, T; Gotoh, T; Cnop, M; Eizirik, DL; Burcelin, Remy; Van Der Schueren, Bart; Mathieu, Chantal
2012 Deletion of C/EBP homologous protein Chop dissociates obesity from insulin resistanceMaris, Michael; Overbergh, Lut; Gysemans, Conny; Waget, Aurelie; Cardozo, A; Gotoh, T; Cnop M; Eizirik, DL; Burcelin, R; Mathieu, Chantal
2012 ORAL L.LACTIS SECRETING HUMAN PRO-INSULIN PLUS IL-10 COMBINED WITH SHORT-TERM LOW-DOSE ANTI-CD3 INDUCES LONG LASTING DIABETES REMISSIONTakiishi, Tatiana; Korf, Hannelie; Van Belle, Tom; Robert, Sofie; Grieco, Fabio; Caluwaerts, Sylvia; Galleri, Letizia; Spagnuolo, Isabella; Steidler, Lothar; Van Huynegem, Karolien; Demetter, Pieter; Wasserfall, Clive; Dotta, Francesco; Rottiers, Pieter; Gysemans, Conny; Mathieu, Chantal
2012 Effects of Vitamin D on Antigen-specific and Antigen-non-specific Immune Modulation: Relevance for Type 1 DiabetesTakiishi, Tatiana; Van Belle, Tom; Gysemans, Conny; Mathieu, Chantal
18-Nov-2011 Vitamin D supports successful low-dose combination therapy with anti-CD3, cyclosporine A and islet transplantation in diabetic NOD miceVan Belle, Tom; Baeke, Femke; Gysemans, Conny; Takiishi, Tatiana; Korf, Hannelie; Candon, Sophie; Chatenoud, Lucienne; Mathieu, Chantal
Nov-2011 1,25-Dihydroxyvitamin D3 alters murine dendritic cell behaviour in vitro and in vivoFerreira, Gabriela B; van Etten, Evelyne; Verstuyf, Annemieke; Waer, Mark; Overbergh, Lut; Gysemans, Conny; Mathieu, Chantal
Nov-2011 Cytokines tumor necrosis factor-{alpha} and interferon-{gamma} induce pancreatic {beta}-cell apoptosis through STAT1-mediated Bim protein activationBarthson, Jenny; Germano, Carla M; Moore, Fabrice; Maida, Adriano; Drucker, Daniel J; Marchetti, Piero; Gysemans, Conny; Mathieu, Chantal; Nunez, Gabriel; Jurisicova, Andrea; Eizirik, Decio L; Gurzov, Esteban N
27-Sep-2011 Calcium Insufficiency Accelerates Type 1 Diabetes in Vitamin D Receptor-Deficient Nonobese Diabetic (NOD) MiceDriver, John P; Lamont, Deanna J; Gysemans, Conny; Mathieu, Chantal; Serreze, David V
15-Aug-2011 Pancreatic beta-cells activate a JunB/ATF3-dependent survival pathway during inflammationGurzov, E N; Barthson, J; Marhfour, I; Ortis, F; Naamane, N; Igoillo-Esteve, M; Gysemans, Conny; Mathieu, Chantal; Kitajima, S; Marchetti, P; Orntoft, T F; Bakiri, L; Wagner, E F; Eizirik, D L
Aug-2011 Vitamin D in autoimmune, infectious and allergic diseases: A vital player?Van Belle, Tom; Gysemans, Conny; Mathieu, Chantal
May-2011 Severe growth plate abnormalities and increased bone volume in mice with chondrocyte-specific inactivation of Forkhead Box O (FOXO) transcription factorsEelen, Guy; Maes, Christa; Gysemans, Conny; Paik, J. -H; DePinho, R; Bouillon, Roger; Carmeliet, Geert; Verstuyf, Annemieke
Feb-2011 Pdx1- and Ngn3-Cre-mediated PLAG1 expression in the pancreas leads to endocrine hormone imbalances that affect glucose metabolismDeclercq, Jeroen; Kumar, Anujith; Gysemans, Conny; Pietro, Caterina Di; Schraenen, Anica; Chintinne, Marie; Lemaire, Katleen; Van Lommel, Leentje; Van de Casteele, Marc; Heimberg, Harry; Pipeleers, Daniel; Schuit, Frans; Mathieu, Chantal; Ectors, Nadine; Van de Ven, Wim; Verfaillie, Catherine
Jan-2011 The Vitamin D Analog, TX527, Promotes a Human CD4+CD25highCD127low Regulatory T Cell Profile and Induces a Migratory Signature Specific for Homing to Sites of InflammationBaeke, Femke; Korf, Hannelie; Overbergh, Lutgart; Verstuyf, Annemieke; Thorrez, Lieven; Van Lommel, Leentje; Waer, Mark; Schuit, Frans; Gysemans, Conny; Mathieu, Chantal
2011 Vitamin D Supports Successful Low-Dose Combination Therapy with Anti-CD3, Cyclosporine A and Islet Transplantation in Diabetic NOD MiceVan Belle, Tom; Baeke, Femke; Gysemans, Conny; Takiishi, Tatiana; Korf, Hannelie; Candon, Sophie; Chatenoud, Lucienne; Mathieu, Chantal
2011 Vitamin D supports successful low-dose combination therapy with anti-CD3, cyclosporine A and islet transplantation in diabetic NOD miceVan Belle, Tom; Baeke, Femke; Gysemans, Conny; Takiishi, Tatiana; Korf, Hannelie; Candon, S; Chatenoud, L; Mathieu, Chantal
2011 Macrophages as cellular targets for immune modulation in experimental autoimmune type I diabetesKorf, Hannelie; Wenes, Mathias; Stijlemans, Benoit; Van Ginderachter, Jo; Murial, Moser; Eizirik, Decio; Overbergh, Lut; Gysemans, Conny; Mathieu, Chantal
2011 Vitamin D and diabetesGysemans, Conny; Korf, Hannelie; Mathieu, Chantal; Feldman, D (othereditor); Glorieux, F.H. (othereditor); Pike, J.W. (othereditor)
Sep-2010 Role of STAT-1 and IRF-1 in cytokine-mediated dysfunction and apoptosis in mouse islets of LangerhansOverbergh, Lut; D'Hertog, Wannes; Gysemans, Conny; Eizirik, D. L; Waelkens, Etienne; Mathieu, Chantal
Aug-2010 Increased beta-cell mass by islet transplantation and PLAG1 overexpression causes hyperinsulinemic normoglycemia and hepatic insulin resistance in miceDeclercq, Jeroen; Kumar, Anujith; Van Diepen, Janna A; Vroegrijk, Irene O C M; Gysemans, Conny; Di Pietro, Caterina; Voshol, Peter J; Mathieu, Chantal; Ectors, Nadine; Van de Ven, Willem; Verfaillie, Catherine
Jun-2010 Vitamin D and diabetesTakiishi, Tatiana; Gysemans, Conny; Bouillon, Roger; Mathieu, Chantal
Jun-2010 Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) MonocytesMovahedi, Kiavash; Laoui, Damya; Gysemans, Conny; Baeten, Martijn; Stangé, Geert; Van den Bossche, Jan; Mack, Matthias; Pipeleers, Daniel; In't Veld, Peter; De Baetselier, Patrick; Van Ginderachter, Jo A
Apr-2010 Vitamin D: modulator of the immune systemBaeke, Femke; Takiishi, Tatiana; Korf, Hannelie; Gysemans, Conny; Mathieu, Chantal
Mar-2010 Human T lymphocytes are direct targets of 1,25-dihydroxyvitamin D(3) in the immune systemBaeke, Femke; Korf, Hannelie; Overbergh, Lut; van Etten, Evelyne; Verstuyf, Annemieke; Gysemans, Conny; Mathieu, Chantal
Feb-2010 Vitamin D insufficiency: implications for the immune systemBaeke, Femke; Gysemans, Conny; Korf, Hannelie; Mathieu, Chantal
2010 Diabetes remission in new-onset diabetic NOD mice by combination low-dose anti-CD3 and L.lactic secreting human pro-insulin plus IL-10Takiishi, Tatiana; Gysemans, Conny; Korf, Hannelie; Steidler, Lothar; Rottiers, Pieter; Mathieu, Chantal
2010 Pathogenesis of Type 1 Diabetes Mellitus: Immunologic PathwaysKorf, Hannelie; Gysemans, Conny; Overbergh, Lut; Mathieu, Chantal
2010 vitamin D analog, TX527, promotes a human CD4+CD25highCD127-/dim regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammationKorf, Hannelie; Baeke, Femke; Overbergh, Lut; Verstuyf, Annemieke; Thorrez, Lieven; Waer, Mark; Schuit, Frans; Gysemans, Conny; Mathieu, Chantal
2010 Prevention of diabetes recurrence after syngeneic islet transplantation in NOD mice by a combination of a vitamin D analog, TX527, anti-CD3 and cyclosporine AGysemans, Conny; Baeke, Femke; Takiishi, Tatiana; Korf, Hannelie; Chatenoud, L; Mathieu, Chantal
2010 1,25-Dihydroxyvitamin D3 alters dendritic cell behavior in vitro and in vivoFerreira, Gabriela B; Korf, Hannelie; van Etten, Evelyne; Overbergh, Lut; Gysemans, Conny; Mathieu, Chantal
Nov-2009 Interferon regulatory factor-1 is a key transcription factor in murine beta cells under immune attackGysemans, Conny; Callewaert, Hanne; Moore, F; Nelson-Holte, Molly; Overbergh, Lutgart; Eizirik, D; Mathieu, Chantal
Jun-2009 Molecular Evolution of a Novel Hyperactive Sleeping Beauty Transposase Enables Robust Stable Gene Transfer in VertebratesMates, L; Chuah, Marinee; Belay, Eyayu; Jerchow, Boris; Manoj, Namitha; Acosta Sanchez, Abel; Judis, C; Schmitt, Andrea; Matrai, J; Ma, L; Samara, Ermira; Gysemans, Conny; Pryputniewicz, Diana; Fletcher, Bradley; Vandendriessche, Thierry; Ivics, Zoltan; Izsvak, Zsuzsanna
2009 Synergistic Modulation of Human DC Phenotype and Function by Vitamin D Analogue and Histone Deacetylase InhibitorFerreira, Gabriela B; Gysemans, Conny; van Etten, Evelyne; Waelkens, Etienne; Mascagni, Paolo; Overbergh, Lutgart; Mathieu, Chantal
2009 Combination Therapy of Short-term Low-dose Anti-CD3 and Oral Administration of Genetically-modified Lactococcus Lactis Secreting Insulin and IL-10 Enhances Remission in New-onset Diabetic NOD MiceTakiishi, Tatiana; Gysemans, Conny; Snoeck, Veerle; Steidler, Lothar; Chatenoud, Lucienne; Rottiers, Pieter; Mathieu, Chantal
Dec-2008 Vitamin D signaling in immune-mediated disorders: Evolving insights and therapeutic opportunitiesBaeke, Femke; van Etten, Evelyne; Gysemans, Conny; Overbergh, Lutgart; Mathieu, Chantal
Oct-2008 Regulation of vitamin D homeostasis: implications for the immune systemvan Etten, Evelyne; Stoffels, Katinka; Gysemans, Conny; Mathieu, Chantal; Overbergh, Lutgart
Aug-2008 Pancreatic duct cells in human islet cell preparations are a source of angiogenic cytokines interleukin-8 and vascular endothelial growth factorMovahedi, Babak; Gysemans, Conny; Jacobs-Tulleneers-Thevissen, Daniel; Mathieu, Chantal; Pipeleers, Daniel
24-Jun-2008 Beta-cell death in Type 1 Diabetes: How can we makestronger beta-cells?Callewaert, Hanne; Mathieu, Chantal (supervisor); Gysemans, Conny (cosupervisor)
Jun-2008 Cytokine signalling in the beta-cell: a dual role for IFN gammaGysemans, Conny; Callewaert, Hanne; Overbergh, Lutgart; Mathieu, Chantal
May-2008 Late CD8+ T cell-dependent xenoantibody production in innate tolerant nude rats after hamster islet grafting but not after hamster heart graftingDevos, Timothy; Li, Shengqiao; Gysemans, Conny; Yan, Yehong; Van Damme, Boudewijn; Nelson-Holte, Molly; Billiau, An; Waer, Mark; Mathieu, Chantal
May-2008 Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathwaysDogusan, Zeynep; García, Mónica; Flamez, Daisy; Alexopoulou, Lena; Goldman, Michel; Gysemans, Conny; Mathieu, Chantal; Libert, Claude; Eizirik, Decio Laks; Rasschaert, Joanne
Apr-2008 Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activityMovahedi, Kiavash; Guilliams, Martin; Van den Bossche, Jan; Van den Bergh, Rafael; Gysemans, Conny; Beschin, Alain; De Baetselier, Patrick; Van Ginderachter, Jo A
Mar-2008 Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T-CELL suppressive activityMovahedi, Kiavash; Guiliams, Martin; Van den Bossche, Jan; Van den Bergh, Rafael; Gysemans, Conny; Beschin, Alain; De Baetselier, Patrick; Van Ginderachter, Jo A
Jan-2008 Unaltered diabetes presentation in NOD mice lacking the vitamin D receptorGysemans, Conny; van Etten, Evelyne; Overbergh, Lutgart; Giulietti, Annapaula; Eelen, Guy; Waer, Mark; Verstuyf, Annemieke; Bouillon, Roger; Mathieu, Chantal
2008 Targeting inflammation in experimental islet transplantationMaris, Michael; Gysemans, Conny; Overbergh, Lut; D'Hertog, Wannes; Mathieu, Chantal
Dec-2007 Proteomics analysis of cytokine-induced dysfunction and death in insulin producing INS-1E cells: new insights into the pathways involvedD'Hertog, Wannes; Overbergh, Lutgart; Lage, Kasper; Ferreira, Gabriela B; Maris, Michael; Gysemans, Conny; Flamez, Daisy; Cardozo, Alessandra Kupper; Van den Bergh, Gert; Schoofs, Liliane; Arckens, Lut; Moreau, Yves; Hansen, Daniel Aaen; Eizirik, Decio Laks; Waelkens, Etienne; Mathieu, Chantal
Nov-2007 Proteomic analysis of cytokine-induced dysfunction and death in ins-1E cells: New insights into the pathways involvedOverbergh, Lutgart; D'Hertog, Wannes; Lage, Karl; Gysemans, Conny; Cardozo, Alessandra Kupper; Hansen, D. A; Eizirik, Decio Laks; Waelkens, Etienne; Mathieu, Chantal
Nov-2007 Improving survival and function of pancreatic islets using an adenoviral-driven super-repressor of NF-kappa B activityGysemans, Conny; Callewaert, Hanne; Hagenbrock, Julianna; Rasschaert, Joanne; Lortz, Stephan; Eizirik, Decio Laks; Mathieu, Chantal
Sep-2007 Early mediators and downstream effectors of dsRNA-induced beta cell apoptosis: The role of IRF-3 and ER stressRasschaert, Joanne; Dogusan, Zeynep; Garcia, Monica; Flamez, Daisy; Alexopoulou, Lena; Goldman, Michel; Gysemans, Conny; Mathieu, Chantal; Libert, Claude; Eizirik, Decio Laks
Sep-2007 Differentiation of bone marrow derived rat multipotent adult progenitor cells into pancreatic progenitor cellsBarajas, Miguel; Heremans, Yves; Nelson-Holte, Molly; Esguerra, Camila; Breyer, April; Gysemans, Conny; Fraga, D; Abdul, M; Bansal-Pakala, P; Mathieu, Chantal; Hering, Bernard; Verfaillie, Catherine
12-Aug-2007 Cell loss during pseudoislet formation hampers profound improvements in islet lentiviral transduction efficacy for transplantation purposesCallewaert, Hanne; Gysemans, Conny; Cardozo, Alessandra Kupper; Elsner, Matthias; Tiedge, Markus; Eizirik, Decio Laks; Mathieu, Chantal
Aug-2007 Deletion of STAT-1 pancreatic islets protects against streptozotocin-induced diabetes and early graft failure but not against late rejectionCallewaert, Hanne; Gysemans, Conny; Ladrière, Laurence; D'Hertog, Wannes; Hagenbrock, Julianna; Overbergh, Lutgart; Eizirik, Decio L; Mathieu, Chantal
20-Jul-2007 Mechanism and Potential of the Growth-Inhibitory Actions of Vitamin D and Ana-logsEelen, Guy; Gysemans, Conny; Verlinden, Lieve; Vanoirbeek, Els; De Clercq, P; Van Haver, D; Mathieu, Chantal; Bouillon, Roger; Verstuyf, Annemieke
Jul-2007 The role of vitamin D in the pathogenesis of NOD mouse diabetesGysemans, Conny; Decallonne, Brigitte; van Etten, Evelyne; Mathieu, Chantal
Apr-2007 Protective role of IFN-{gamma} in collagen-induced arthritis conferred by inhibition of mycobacteria-induced granulocyte chemotactic protein-2 (GCP-2) productionKelchtermans, Hilde; Struyf, Sofie; De Klerck, Bert; Mitera, Tania; Alen, Marijke; Geboes, Lies; Van Balen, Maarten; Dillen, Christiane; Put, Willy; Gysemans, Conny; Billiau, Alfons; Van Damme, Jozef; Matthys, Patrick
Mar-2007 Novel insights in the immune function of the vitamin D system: Synergism with interferon-betavan Etten, Evelyne; Gysemans, Conny; Branisteanu, Dumitru; Verstuyf, Annemieke; Bouillon, Roger; Overbergh, Lutgart; Mathieu, Chantal
Sep-2006 Viral transduction efficiency and gene expression in pseudo-islet aggregates with HIV-based lentiviral vectors: in vitro and in vivo analysisCallewaert, Hanne; Gysemans, Conny; Cardozo, Alessandra Kupper; Elsner, Matthias; Tiedge, Markus; Eizirik, Decio Laks; Mathieu, Chantal
Sep-2006 Unaltered development of insulitis and diabetes in vitamin D receptor KO NOD miceGysemans, Conny; van Etten, Evelyne; Overbergh, Lutgart; Giulietti, Annapaula; Eelen, Guy; Bouillon, Roger; Verstuyf, Annemieke; Mathieu, Chantal
Jan-2006 Quantification of chemokines by real-time reverse transcriptase PCR: applications in type 1 diabetesOverbergh, Lutgart; Gysemans, Conny; Mathieu, Chantal
2006 Vitamin D and diabetesMathieu, Chantal; Gysemans, Conny
Oct-2005 Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cellsRasschaert, Joanne; Ladrière, Laurence; Urbain, Maryse; Dogusan, Zeynep; Katabua, Bitty; Sato, Shintaro; Akira, Shizuo; Gysemans, Conny; Mathieu, Chantal; Eizirik, Décio L
Sep-2005 Development of xenotolerance in (CD4+ or CD8+) T-dependent B lymphocytes after their exposure to xenoantigens in the absence of T lymphocytesDevos, Timothy; Laureys, Jozef; Li, SG; Rutgeerts, O; Gysemans, Conny; Yan, YH; Lin, Yuan; Van Damme, B; Mathieu, Chantal
Aug-2005 Disruption of the gamma-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cellsGysemans, Conny; Ladrière, Laurence; Callewaert, Hanne; Rasschaert, Joanne; Flamez, Daisy; Levy, David E; Matthys, Patrick; Eizirik, Décio L; Mathieu, Chantal
5-Jul-2005 Vitamin D and diabetesMathieu, Chantal; Gysemans, Conny; Giulietti, Annapaula; Bouillon, Roger
Apr-2005 1,25-Dihydroxyvitamin D3 modulates expression of chemokines and cytokines in pancreatic islets: implications for prevention of diabetes in nonobese diabetic miceGysemans, Conny; Cardozo, Alessandra K; Callewaert, Hanne; Giulietti, Annapaula; Hulshagen, Leen; Bouillon, Roger; Eizirik, Décio L; Mathieu, Chantal
Jan-2005 Role of CD4+ and CD8+ T cells in the rejection of heart or islet xenografts in recipients with xenotolerance in the innate immune compartmentDevos, Timothy; Yan, Yan; Segers, Constant; Rutgeerts, Omer; Laureys, Jozef; Gysemans, Conny; Mathieu, Chantal; Waer, Mark
2005 Blocking IFN-gamma signaling cascade in islets alters their chemokine expression, but is insufficient for protection in vivoCallewaert, Hanne; Gysemans, Conny; Ladiere, Laurence; Laureys, Jozef; Valckx, Dirk; Overbergh, Lutgart; Eizirik, Decio Laks; Mathieu, Chantal
2005 Toll-like receptor 3 and STAT-1 contribute for dsRNA plus IFN-gamma-induced apoptosis in pancreatic beta cellsRasschaert, J; Ladriere, L; Dogusan, Z; Sato, S; Akira, S; Gysemans, Conny; Mathieu, Chantal; Eizirik, DL
2005 Vitamin D and diabetesMathieu, Chantal; Gysemans, Conny; Bouillon, Roger; Feldman, D. (othereditor); Pike, F.H. (othereditor); Glorieux, J.W. (othereditor)
2005 Regulation of cytokines and immune function by 1,25-dihydroxyvitamin D3 and its analoguesvan Etten, Evelyne; Giulietti, Annapaula; Gysemans, Conny; Verstuyf, Annemieke; Overbergh, Lutgart; Mathieu, Chantal; Zempleni, J (othereditor); Dakshinamurti, K (othereditor)
Dec-2004 1,25-Dihydroxyvitamin D3 alters the profile of bone marrow-derived dendritic cells of NOD micevan Etten, Evelyne; Dardenne, Olivier; Gysemans, Conny; Overbergh, Lutgart; Mathieu, Chantal
6-Jul-2004 NOD macrophages produce high levels of inflammatory cytokines upon encounter of apoptotic or necrotic cellsStoffels, Katinka; Overbergh, Lutgart; Giulietti, Annapaula; Kasran, Ahmad; Bouillon, Roger; Gysemans, Conny; Mathieu, Chantal
6-Jun-2004 Vitamin D and 1,25-dihydroxyvitamin D3 as modulators in the immune systemMathieu, Chantal; van Etten, Evelyne; Decallonne, Brigitte; Giulietti, Annapaula; Gysemans, Conny; Bouillon, Roger; Overbergh, Lutgart
Jun-2004 Monocytic mRNA expression of immune markers in diabetic patientsGiulietti, Annapaula; Stoffels, Katinka; Gysemans, Conny; Overbergh, Lutgart; Mathieu, Chantal
6-Mar-2004 Vitamin D deficiency in early life accelerates Type 1 diabetes in non-obese diabetic miceGiulietti, Annapaula; Gysemans, Conny; Stoffels, Katinka; van Etten, Evelyne; Decallonne, Brigitte; Overbergh, Lutgart; Bouillon, Roger; Mathieu, Chantal
Aug-2003 Prevention of primary non-function of islet xenografts in autoimmune diabetic NOD mice by anti-inflammatory agentsGysemans, Conny; Stoffels, Katinka; Giulietti, Annapaula; Overbergh, Lutgart; Waer, Mark; Lannoo, Matthias; Feige, Ulrich; Mathieu, Chantal
Jun-2003 Vitamin D deficiency increases type 1 diabetes incidence in NOD miceMathieu, Chantal; Giulietti, Annapaula; Gysemans, Conny; van Etten, Evelyne; Stoffels, Katinka; Decallonne, Brigitte; Bouillon, Roger
6-Mar-2003 IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD miceCardozo, Alessandra K; Proost, Paul; Gysemans, Conny; Chen, M-C; Mathieu, Chantal; Eizirik, Décio L
Aug-2002 Interleukin-1 receptor antagonist inhibits primary non-function and prolongs graft survival time of xenogeneic islets transplanted in spontaneously diabetic autoimmune NOD miceStoffels, Katinka; Gysemans, Conny; Waer, Mark; Laureys, Jozef; Bouillon, Roger; Mathieu, Chantal
Aug-2002 Inhibition of primary non-function and prolongation of graft survival of xenogeneic islets by non-steroidal anti-inflammatory agents in non-obese diabetic mice: correlation with diminished non-T-cell cytokines in the grafts and suppression of plasma nitrite productionGysemans, Conny; Stoffels, Katinka; Laureys, Jozef; Valckx, Dirk; Waer, Mark; Bouillon, Roger; Mathieu, Chantal
Aug-2002 1L-1 beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD miceCardozo, AK; Proost, Paul; Gysemans, Conny; Chen, M; Mathieu, Chantal; Eizirik, DL
May-2002 Treatment of autoimmune diabetes recurrence in non-obese diabetic mice by mouse interferon-beta in combination with an analogue of 1alpha,25-dihydroxyvitamin-D3Gysemans, Conny; van Etten, Evelyne; Overbergh, Lutgart; Verstuyf, Annemieke; Waer, Mark; Bouillon, Roger; Mathieu, Chantal
Apr-2002 Seasonality of birth in patients with type 1 diabetesMathieu, Chantal; van Etten, Evelyne; Gysemans, Conny; Decallonne, Brigitte; Bouillon, Roger
Nov-2001 In vitro and in vivo analysis of the immune system of vitamin D receptor knockout miceMathieu, Chantal; van Etten, Evelyne; Gysemans, Conny; Decallonne, Brigitte; Kato, Shigeaki; Laureys, Jozef; Depovere, Jos; Valckx, Dirk; Verstuyf, Annemieke; Bouillon, Roger
6-May-2001 Immunomodulatory properties of a 1,25(OH)(2) vitamin D(3) analog combined with IFNbeta in an animal model of syngeneic islet transplantationvan Etten, Evelyne; Gysemans, Conny; Verstuyf, Annemieke; Bouillon, Roger; Mathieu, Chantal
May-2001 A combination of KH1060, a vitamin D(3) analogue, and cyclosporin prevents early graft failure and prolongs graft survival of xenogeneic islets in nonobese diabetic miceGysemans, Conny; Waer, Mark; Laureys, Jozef; Bouillon, Roger; Mathieu, Chantal
May-2001 Leflunomide and its analogue X920715 synergize with cyclosporin A in preventing early graft failure and delaying graft rejection of xenogeneic islets in nonobese diabetic miceGysemans, Conny; Waer, Mark; Laureys, Jozef; Bouillon, Roger; Mathieu, Chantal
May-2001 Dual role of interferon-gamma signalling pathway in sensitivity of pancreatic beta cells to immune destructionGysemans, Conny; Pavlovic, Dejan; Bouillon, Roger; Eizirik, Decio Laks; Mathieu, Chantal
6-Apr-2001 Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 beta-exposed human and rat islet cellsChen, M C; Proost, Paul; Gysemans, Conny; Mathieu, Chantal; Eizirik, Décio L
2001 Immunomodulatory properties of a 1,25(OH)(2) vitamin D(3) analog combined with IFNbeta in an animal model of syngeneic islet transplantationvan Etten, Evelyne; Gysemans, Conny; Verstuyf, Annemieke; Bouillon, Roger; Mathieu, Chantal
Dec-2000 Early graft failure of xenogeneic islets in NOD mice is accompanied by high levels of interleukin-1 and low levels of transforming growth factor-beta mRNA in the graftsGysemans, Conny; Waer, Mark; Valckx, Dirk; Laureys, Jozef; Mihkalsky, D; Bouillon, Roger; Mathieu, Chantal
Oct-2000 Streptococcal wall component OK432 restores sensitivity of non-obese diabetic (NOD) thymocytes to apoptotic signalsDecallonne, Brigitte; Overbergh, Lutgart; Casteels, Kristina; Gysemans, Conny; Bouillon, Roger; Mathieu, Chantal
Sep-2000 Islet xenograft destruction in the hu-PBL-severe combined immunodeficient (SCID) mouse necessitates anti-CD3 preactivation of human immune cellsGysemans, Conny; Waer, Mark; Laureys, Jozef; Depovere, Jos; Pipeleers, Daniel; Bouillon, Roger; Mathieu, Chantal
Aug-2000 Expression of the monocyte chemoattractant protein-1 (MCP-1) in rat and human islet cells and in pre-diabetic NOD miceChen, MC; Proost, Paul; Gysemans, Conny; Mathieu, Chantal; Eizirik, Decio Laks
May-2000 Disruption of the interferon regulatory factor-1 (IRF-1) pathway renders islets more susceptible to allograft rejection and multiple low-dose streptozotocin-induced diabetesMathieu, Chantal; Gysemans, Conny; Pavlovic, Dejan; Eizirik, Decio Laks; Bouillon, Roger
2000 Immunomodulatory effects of a 14-epi-1,25(OH)2vitamin D3 analog in combination with IFN-β and cyclosporin A in an animal model of syngeneic islet transplantationvan Etten, Evelyne; Gysemans, Conny; Laureys, Jozef; Verstuyf, Annemieke; Bouillon, Roger; Mathieu, Chantal; Norman, AW (othereditor); Bouillon, R (othereditor); Thomasset, M (othereditor)
6-Oct-1999 The role of interferon regulatory factor-1 in cytokine-induced mRNA expression and cell death in murine pancreatic beta-cellsPavlovic, Dejan; Chen, M C; Gysemans, Conny; Mathieu, Chantal; Eizirik, Décio L
Aug-1999 Primary nonfunction of islet xenografts in spontaneously diabetic autoimmune NOD mice: Correlation with elevated non-T cell cytokines in the graftsMathieu, Chantal; Gysemans, Conny; Laureys, Jozef; Depovere, Jos; Waer, Mark; Bouillon, Roger
Aug-1999 The hu-PBL-SCID mouse as model for islet xenotransplantationGysemans, Conny; Laureys, Jozef; Depovere, Jos; Waer, Mark; Bouillon, Roger; Mathieu, Chantal
Apr-1999 Primary nonfunction of islet xenografts spontaneously diabetic autoimmune NOD mice: Correlation with elevated non-T cell cytokines and Fas-L expression of the graftsGysemans, Conny; Laureys, Jozef; Valckx, Dirk; Bouillon, Roger; Waer, Mark; Mathieu, Chantal
Apr-1999 Xenogeneic islet graft destruction in the human SCID mouse model can only be achieved by human preactivated immune cellsGysemans, Conny; Laureys, Jozef; Depovere, Jos; Bouillon, Roger; Waer, Mark; Mathieu, Chantal
Jul-1998 Sex difference in resistance to Dexamethasone-induced apoptosis in NOD mice: treatment with 1,25(OH)2D3 restores defectCasteels, Kristina; Gysemans, Conny; Waer, Mark; Bouillon, Roger; Laureys, Jozef; Depovere, Jos; Mathieu, Chantal
May-1998 Effect of sex hormones on apoptosis in NOD mice: Link to autoimmunityCasteels, Kristina; Gysemans, Conny; Waer, Mark; Bouillon, Roger; Depovere, Jos; Laureys, Jozef; Mathieu, Chantal
May-1998 Prevention of PNF and prolongation of graft survival in rat islet xenografts in autoimmune NOD mice by a combination of leflunomide and cyclosporine AGysemans, Conny; Mikhalsky, Dimitru; Laureys, Jozef; Waer, Mark; Bouillon, Roger; Mathieu, Chantal
6-Oct-1996 The use of intermittent lighting in broiler raising. 2. Effects on the somatotrophic and thyroid axes and on plasma testosterone levelsKühn, Eduard; Darras, Veerle; Gysemans, Conny; Decuypere, Eddy; Berghman, L R; Buyse, Johan