Elife
Publication date:
2022-11-03
Volume:
11
DOI:
10.7554/eLife.83907
Publisher:
eLIFE SCIENCES PUBL LTD
Author:
Ozguc, Olivia
Vonesch, Sibylle
Keywords:
Science & Technology, Life Sciences & Biomedicine, Biology, Life Sciences & Biomedicine - Other Topics, S. cerevisiae, base editor, chromosomes, crispr screen, gapdh isoenzymes, gene expression, gene regulatory network, genetics, genomics, protein regulation, ras/pka, Gene Expression Regulation, Fungal, Saccharomyces cerevisiae, 0601 Biochemistry and Cell Biology, 31 Biological sciences, 32 Biomedical and clinical sciences, 42 Health sciences
Abstract:
A new pooled screening method in yeast allows scientists to probe how protein levels are regulated by mutating thousands of genes at once.