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Title: Effect of external K on the block of the inward rectifier during hyperpolarization in guinea-pig ventricular myocytes by external Na
Authors: Biermans, G ×
Vereecke, Johan
Carmeliet, Edward #
Issue Date: Sep-1989
Series Title: Biomedica biochimica acta. vol:48 issue:5-6 pages:S358-63
Abstract: The effect of changes of the external K concentration on the block of the inward-rectifying K current during hyperpolarization in guinea-pig ventricular myocytes by external Na was investigated. The voltage-dependent block of iK1 by external Na ions is decreased when the external K concentration is lowered between 5.4 and 0.54 mM, but is not influenced when Ko is increased from 5.4 to 27 mM. The effect of lowering Ko can be described as a decrease of the rate of entry of blocking Na ions at lower external K.
ISSN: 0232-766X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Physiology Section (-)
Laboratory of Molecular and Cellular Signaling
Department of Cellular and Molecular Medicine - miscellaneous
× corresponding author
# (joint) last author

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