Title: [Potentiation and staircase phenomena in rabbit heart atrium and their connection with inotropic vague effects]
Authors: Koester, G ×
Nilius, Bernd #
Issue Date: Feb-1981
Series Title: Acta biologica et medica Germanica. vol:39 issue:5 pages:513-23
Abstract: At spontaneously beating rabbit atria in vitro longtime pauses of contraction were produced by vagal stimulation. After finishing the stimulation at once contractions took place; the first of them was potentiated. During the vagal pauses various beat interval programs were realized. After removing the sinusoidal node the same programs were repeated by variation of drive interval length. Their effects were compared to the effects in vagal pauses. All these effects were simulated by a two stores three phases model. This model allows description of potentiation and staircase phenomena as well as inotropic vagal effect and inotropic vagal escape. It suggests a connection between this two kinds of phenomena.
ISSN: 0001-5318
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Ion Channel Research (VIB-KU Leuven Center for Brain & Disease Research)
Department of Cellular and Molecular Medicine - miscellaneous
× corresponding author
# (joint) last author

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