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Title: Interaction of myelin basic protein with the different components of the ATP,Mg-dependent protein phosphatase system
Authors: Vandenheede, Jackie ×
Van Lint, Johan
Vanden Abeele, Carline
Merlevede, Wilfried #
Issue Date: Mar-1987
Publisher: Elsevier science bv
Series Title: FEBS Letters vol:211 issue:2 pages:190-194
Abstract: Myelin basic protein (MBP) reduces the amount of phosphatase activity produced in the kinase FA-mediated activation of the ATP,Mg-dependent phosphatase. MBP was shown not only to inhibit the activated enzyme, but also to impair the kinase FA-mediated activation of the inactive phosphatase. In addition MBP prevents the time-dependent inactivation of the catalytic subunit by the modulator protein. These observations point to a regulatory role for MBP in the reversible activation of the ATP,Mg-dependent protein phosphatase by kinase FA.
ISSN: 0014-5793
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Protein Phosphorylation and Proteomics
Biochemistry Section (Medicine) (-)
× corresponding author
# (joint) last author

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