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Title: Coexistence of light chain disease and chronic lymphocytic leukaemia, a complex karyotype with a rapid fatal outcome
Authors: Castryck, H ×
Van Den Driessche, Mieke
Hagemeijer-Hausman, Anne
Stul, Michel
Wynendaele, Wim
Vandenberghe, Peter
Moerman, John #
Issue Date: Apr-2006
Series Title: Clinical and laboratory haematology. vol:28 issue:2 pages:138-40
Abstract: We report on a 48-year-old man with concomitantly diagnosed kappa expressing chronic lymphocytic leukaemia (CLL) and lambda light chain disease with highly complex chromosomal aberrations. The clinical course of the disease was very aggressive with survival of only 1 month. We demonstrate the distinct clonal origin by cytogenetic data and immunoglobulin rearrangement studies. To our knowledge this is the first report of a light chain disease associated with CLL.
ISSN: 0141-9854
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Section Child - Miscellaneous (-)
Clinical Genetics Section (-)
Department of Human Genetics - miscellaneous
× corresponding author
# (joint) last author

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