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Title: The short arm of chromosome 6 is nonrandomly rearranged in secondary myelodysplastic syndromes
Authors: Mecucci, Christina ×
Michaux, J L
Louwagie, Andries
Boogaerts, Marc
Van den Berghe, Herman #
Issue Date: Apr-1988
Series Title: Cancer genetics and cytogenetics. vol:31 issue:2 pages:147-55
Abstract: Eight patients with a myelodysplastic syndrome showed a structural rearrangement of the short arm of chromosome #6 involving the distal segment 6p22----6pter. In four cases the myelodysplastic disorder appeared after treatment with chemo- and/or radiotherapy. Cytogenetically, the 6p anomaly was consistently associated with abnormalities of chromosome #5 and/or #7 in seven of eight cases. We believe we identified a new site on 6p that is nonrandomly involved in iatrogenically and possibly also environmentally induced malignant hematologic disorders.
ISSN: 0165-4608
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Hematology Section (-)
Clinical Genetics Section (-)
Clinical Genetics
× corresponding author
# (joint) last author

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