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Title: Consecutive glioblastoma and B cell non-Hodgkin's lymphoma in a young child with von Recklinghausen's Neurofibromatosis
Authors: Uyttebroeck, A ×
Legius, Eric
Brock, Penelope
Van de Cassey, W
Casaer, Paul
Casteels-Van Daele, M #
Issue Date: Dec-1994
Series Title: Medical and pediatric oncology. vol:24 issue:1 pages:46-9
Abstract: A young child with neurofibromatosis type 1 (NF1) is reported who developed two primary malignancies: a glioblastoma, followed 6 months later by an abdominal B cell non-Hodgkin's lymphoma. The child is now 4.5 years off treatment and disease free, but has developed progressive and severe psychomotor retardation as sequelae. The NF1 gene is known to act as a tumor suppressor gene. The possible mechanisms leading to the occurrence of a second primary tumor in this child are discussed.
ISSN: 0098-1532
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Clinical Genetics Section (-)
Section Child - Miscellaneous (-)
Department of Human Genetics - miscellaneous
× corresponding author
# (joint) last author

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