Title: Established cell lines used in cystic fibrosis research
Authors: Gruenert, D C ×
Willems, M
Cassiman, Jean-Jacques
Frizzell, R A #
Issue Date: Oct-2004
Series Title: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. vol:3 Suppl 2 pages:191-6
Abstract: The development of immortalized cell lines has been a significant benefit to the study of human disease, due to limitations in using primary cells and the availability of tissue. The immortalization of cells from cystic fibrosis (CF) patients as well as cells from non-CF individuals from tissues relevant to CF has been critical to enhancing our understanding of the physiological, biochemical and genetic mechanisms underlying CF and for the development of therapeutic strategies designed to manage CF pathology. A comprehensive list of immortalized cells from various tissue and species, with an emphasis on epithelial cells, is presented and discussed here.
ISSN: 1569-1993
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Human Mutations and Polymorphisms Section (-)
Forensic Biomedical Sciences
× corresponding author
# (joint) last author

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