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Title: Lack of association between HLA class II polymorphisms and essential hypertension in a Belgian population
Authors: Gu, X X ×
Spaepen, Marijke
Raeymaekers, P
Guo, C
Fagard, Robert
Amery, A
Lijnen, Paul
Cassiman, Jean-Jacques #
Issue Date: Nov-1995
Series Title: Journal of human hypertension. vol:9 issue:7 pages:553-5
Abstract: The aim of the present study was to investigate whether the HLA class II polymorphisms contributes to the susceptibility to essential hypertension in the Belgian population. For this purpose we studied 120 hypertensive patients and 168 normotensive controls by means of a PCR-SSO assay. No significant difference in allele and genotype frequencies of the DRB and DPB1 loci could be found between the two groups. We concluded that essential hypertension as a multifactorial and heterogeneous disease cannot be associated with one of the HLA class II DRB and DPB1 alleles in Belgian patients.
ISSN: 0950-9240
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Hypertension and Cardiovascular Epidemiology
Human Mutations and Polymorphisms Section (-)
Forensic Biomedical Sciences
× corresponding author
# (joint) last author

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