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Title: Phytohemagglutinin-conditioned medium modulates adherence properties and morphology of hairy cells
Authors: Mecucci, Christina
Cassiman, Jean-Jacques
Van der Schueren, Bernadette
Peeters, Christiane
Falini, B
Van den Berghe, Herman #
Issue Date: Nov-1986
Series Title: Leukemia research. vol:10 issue:9 pages:1091-9
Abstract: The effect of a PHA-conditioned medium was tested on a population highly enriched in hairy cells obtained from spleens of patients with hairy cell leukemia. Under PHA-CM treatment hairy cells adhered to both plastic and glass and spread assuming a typical stellate shape, without changing their enzymatic and antigenic properties. Provided PHA-CM was present, stellate adherent hairy cells remained viable in culture for several months. Mononuclear splenic cells from patients with various hematological disorders never showed similar phenotypic modifications after PHA-CM treatment.
ISSN: 0145-2126
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Human Mutations and Polymorphisms Section (-)
Translational Cell & Tissue Research
Clinical Genetics Section (-)
Forensic Biomedical Sciences
Clinical Genetics
# (joint) last author

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