Title: The amyloid-beta precursor protein: integrating structure with biological function
Authors: Reinhard, Constanze
H├ębert, S├ębastien
De Strooper, Bart # ×
Issue Date: Dec-2005
Publisher: Nature Publishing Group
Series Title: EMBO Journal vol:24 issue:23 pages:3996-4006
Abstract: Proteolytic processing of the amyloid-beta precursor protein (APP) generates the Abeta amyloid peptide of Alzheimer's disease. The biological function of APP itself remains, however, unclear. In the current review, we study in detail the different subdomains of APP and try to assign functional significance to particular structures identified in the protein.
ISSN: 0261-4189
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Genetics Section (-)
Laboratory for the Research of Neurodegenerative Diseases
Department of Human Genetics - miscellaneous
× corresponding author
# (joint) last author

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