Title: Adhesion of Porphyromonas gingivalis to cultured pocket epithelium: mono- and multi-layered
Authors: Papaioannou, W ×
van Steenberghe, Daniel
Cassiman, Jean-Jacques
Dierickx, K
Quirynen, Marc #
Issue Date: Sep-2003
Series Title: Clinical oral investigations. vol:7 issue:3 pages:162-6
Abstract: Adhesion of bacteria to epithelial cells might be influenced by the degree of cell differentiation, as observed in the multi-layering process of epithelial cells. In the present study, the adhesion of a large group of clinical Porphyromonas gingivalis strains (n=11) to in vitro cultured mono- and multi-layers of epithelial cells was examined and compared. The tissue samples originated from 6 patients with chronic adult periodontitis. Porphyromonas gingivalis bacteria adhered more to mono-layers as opposed to the more differentiated multi-layers. Differences between the clinical P. gingivalis strains, however, became obvious only on multi-layers. These partially differentiated cells may also better represent the individual subject variations. Mono-layer cultures, which are simpler to obtain, seem to be less precise. The importance of cell differentiation on bacterial adhesion needs more attention.
ISSN: 1432-6981
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Periodontology
Human Mutations and Polymorphisms Section (-)
Forensic Biomedical Sciences
× corresponding author
# (joint) last author

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