Title: A clonal translocation (7;8)(p13;q11.2) in a leiomyoma of the vulva
Authors: Horton, Elaine ×
Dobin, Sheila M
Debiec-Rychter, Maria
Donner, Ludvik R #
Issue Date: Sep-2006
Series Title: Cancer genetics and cytogenetics. vol:170 issue:1 pages:58-60
Abstract: We present the first case of a vulvar leiomyoma studied by cytogenetics. The tumor formed a 3.0-cm periurethral nodule in a middle-aged woman and was positive for the muscle markers desmin and caldesmon, and for estrogen and progesterone receptors. Its karyotype was 46,XX,t(7;8)(p13;q11.2). This translocation has not been described in previously reported leiomyomas, regardless of their site of origin. The transcription factor PLAG1 gene at 8q12 was not altered by the translocation.
ISSN: 0165-4608
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Clinical Genetics Section (-)
Laboratory for Genetics of Malignant Disorders
× corresponding author
# (joint) last author

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