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Title: Isolation and mapping of a cosmid clone containing the human NAT2 gene
Authors: Franke, Sabine ×
Klawitz, I
Schnakenberg, E
Rommel, B
Van de Ven, Willem
Bullerdiek, J
Schloot, W #
Issue Date: Apr-1994
Series Title: Biochemical and Biophysical Research Communications vol:199 issue:1 pages:52-5
Abstract: The NAT2 gene encodes for a polymorphic arylalkylamine N-acetyltransferase and thus accounts for the human N-acetylation polymorphism. By a NAT2-specific primer set we have screened a human chromosome 8-specific cosmid library. A positive cosmid clone was mapped by fluorescence in situ hybridization to 8p22. The polymerase chain reaction followed by restriction analysis of the PCR product was used to identify allele 2 to be contained in the cosmid clone.
ISSN: 0006-291X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Department of Human Genetics - miscellaneous
× corresponding author
# (joint) last author

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