Title: [Secretases as therapeutic targets for the treatment of Alzheimer's disease]
Authors: Dejaegere, Tim ×
De Strooper, Bart #
Issue Date: Apr-2004
Series Title: Verhandelingen - Koninklijke Academie voor Geneeskunde van België. vol:66 issue:1 pages:29-58; discussion 58-9
Abstract: Alzheimer's disease is the most frequent degenerative disorder of the central nervous system. A focus on the familial, monogenetic disease subtypes has put researchers on the trail of the primary pathogenetic agent, the Abeta-peptide. The production of this peptide is being controlled by a number of proteolytic enzymes commonly known as the "secretases". An intensive study of the molecular and cell biological functions of these secretases is undertaken with the aim of generating drugs to cure Alzheimer's disease.
ISSN: 0302-6469
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Department of Human Genetics - miscellaneous
Molecular Genetics Section (-)
× corresponding author
# (joint) last author

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