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Title: Polymorphism of the tumour necrosis factor beta gene in multiple sclerosis and rheumatoid arthritis
Authors: Vandevyver, Caroline ×
Raus, P
Stinissen, P
Philippaerts, L
Cassiman, Jean-Jacques
Raus, J #
Issue Date: May-1997
Series Title: European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics. vol:21 issue:5 pages:377-82
Abstract: We evaluated the TNF-beta gene polymorphism in two HLA-associated autoimmune diseases, multiple sclerosis (MS) and rheumatoid arthritis (RA). The TNF-beta allele and genotype frequencies were not significantly different in the patient populations, compared to controls. An increased frequency of the TNF-beta*2 allele was observed in HLA-DR2+ vs. HLA-DR2- MS patients. No such association was seen in HLA-DR4+ RA patients.
ISSN: 0960-7420
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Human Mutations and Polymorphisms Section (-)
Forensic Biomedical Sciences
× corresponding author
# (joint) last author

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