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Title: Toward novel HIV-1 integrase binding inhibitors: Molecular modeling, synthesis, and biological studies
Authors: Mugnaini, Claudia
Rajamaki, Suvi
Tintori, Cristina
Corelli, Federico
Massa, Silvio
Witvrouw, Myriam
Debyser, Zeger
Veljkovic, Veljko
Botta, Maurizio # ×
Issue Date: Oct-2007
Publisher: Pergamon Press
Series Title: Bioorganic & Medicinal Chemistry Letters vol:17 issue:19 pages:5370-5373
Abstract: The identification of a novel hit compound as integrase binding inhibitor has been accomplished by means of virtual screening techniques. A small family of structurally related molecules has been synthesized and biologically evaluated with one of the compounds showing an IC(50)=12muM.
URI: 
ISSN: 0960-894X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Virology and Gene Therapy
× corresponding author
# (joint) last author

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