Title: Is 4q13 a recurring breakpoint in solitary fibrous tumors?
Authors: Debiec-Rychter, Maria ×
De Wever, Ivo
Hagemeijer-Hausman, Anne
Sciot, Raphael #
Issue Date: Dec-2001
Series Title: Cancer genetics and cytogenetics. vol:131 issue:1 pages:69-73
Abstract: Solitary fibrous tumor (SFT) is a mesenchymal neoplasm found predominantly in the subpleural region but also in many other body sites. We report a malignant solitary fibrous tumor of the peritoneum with a 47,XY,t(4;9)(q13;p23),+5 karyotype. The chromosome 4q13 breakpoint in the presented and previously published case of pleural solitary fibrous tumor with a 46,XY,t(4;15)(q13;q26) karyotype was further characterized by fluorescence in situ hybridization analysis and localized within the 5-cM interval that was flanked by regions specific to YAC clones 761A7 and 886C11. Chromosome translocations involving chromosome 4q13 may characterize a separate cytogenetic subgroup of SFT.
ISSN: 0165-4608
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Surgical Oncology
Translational Cell & Tissue Research
Clinical Genetics Section (-)
Laboratory for Genetics of Malignant Disorders
× corresponding author
# (joint) last author

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