Title: A successful strategy for the production of cationic magnetoliposomes
Authors: De Cuyper, Marcel
Caluwier, D
Baert, Johan
Cocquyt, J
Van der Meeren, P #
Issue Date: 2006
Publisher: Oldenbourg verlag
Series Title: Zeitschrift fur physikalische chemie-international journal of research in physical chemistry & chemical physics vol:220 issue:1 pages:133-141
Abstract: The present work describes a strategy and the mechanistic background for synthesizing magnetoliposomes (MLs) in which the bi-layered coating is partly composed of positively charged lipids. In a first step, neutral MLs are prepared from zwitterionic phosphatidylcholine vesicles and magnetite nanocores stabilized with an anionic surfactant, and then incubated with cationic vesicles formed from phosphatidylcholine and dioleoyltrimethyl-ammoniumpropane. During this latter step, spontaneous intermembrane lipid transfer occurs. After reaching an equilibrium state, the desired cationic MLs are captured from the mixture in a high-gradient magnetophoresis setup.
ISSN: 0942-9352
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Faculty of Medicine, Campus Kulak Kortrijk
# (joint) last author

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