Recurrence of blackwater fever: triggering of relapses by different antimalarials
Van den Ende, J Coppens, G Verstraeten, T Van Haegenborgh, T Depraetere, K Van Gompel, A Van den Enden, E Clerinx, Jacques Colebunders, R Peetermans, Willy Schroyens, W #
Blackwell science ltd
Tropical medicine & international health vol:3 issue:8 pages:632-639
Five cases of blackwater fever (BWF) are described, all of whom had a history of recent quinine therapy In two cases a second haemolytic crisis was induced by halofantrine, in one case also a third. increasing frequency of this syndrome with its dramatic clinical presentation is to be expected as imported P. falciparum infection, parasite resistance to chloroquine and the use of quinine and other related antimalarials become more frequent.