Alpha-1-proteinase inhibitor gene frequencies in Belgium
Kimpen, J × Legius, Eric Bosmans, E Van Vaerenbergh, V Ramon, A Raus, J #
Gene geography : a computerized bulletin on human gene frequencies. vol:4 issue:3 pages:159-63
The alpha-1-antitrypsin phenotype was determined in cord blood of 1345 Belgian newborns by isoelectric focusing in polyacrylamide gels. Proteinase inhibitor (PI) gene frequencies were calculated. The relative gene frequency of the M allele was 0.9245, and those of S and Z alleles were 0.0543 and 0.0167 respectively. I and F alleles were less represented. These results are in agreement with population studies of neighbouring countries.