Title: Mycobacterium smegmatis has two pyrazinamidase enzymes, PncA and PzaA
Authors: Guo, M
Sun, ZH
Zhang, Ying #
Issue Date: Jul-2000
Publisher: Amer soc microbiology
Series Title: Journal of bacteriology vol:182 issue:13 pages:3881-3884
Abstract: The Mycobacterium smegmatis pncA gene, encoding nicotinamidase/pyrazinamidase, was identified. While it was similar to counterparts from other mycobacteria, the M. smegmatis PncA had little homology to the other M. smegmatis pyrazinamidase/nicotinamidase, encoded by the pzaA gene. Transformation of Mycobacterium bovis strain BCG with M. smegmatis pncA or pzaA conferred susceptibility to pyrazinamide.
ISSN: 0021-9193
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
# (joint) last author

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