Title: Hereditary retinal dystrophies and choroidal neovascularization
Authors: Marano, F ×
Deutman, AF
Leys, Anita
Aandekerk, AL #
Issue Date: Sep-2000
Publisher: Springer-verlag
Series Title: Graefes archive for clinical and experimental ophthalmology vol:238 issue:9 pages:760-764
Abstract: Background: Choroidal neovascularization infrequently occurs in patients affected by hereditary retinal dystrophies. Methods: We studied eight patients suffering from different hereditary retinal dystrophies (Best's disease, reticular dystrophy, butterfly-shaped dystrophy, gyrate atrophy, and retinitis pigmentosa) who developed choroidal neovascularization. All patients underwent complete ophthalmic evaluation, electrophysiology, colour vision testing, and fluorescein angiography. In some patients, ICG video-angiography was also performed. Laser treatment was carried out in only one patient. Results: The mean duration of follow-up was 41.7 months (range 6-148 months). At CNV diagnosis, the mean VA was 0.23 (range 0.02-0.6), At the last follow-up, mean VA was 0.34 (range HM to 0.9). At the last follow-up, fluorescein angiography showed a focal, atrophic scar in seven eyes, a fibrotic membrane in two eyes and a still active membrane in two cases. Conclusion: We emphasize the relatively favourable visual prognosis in patients suffering from inherited retinal dystrophies complicated with choroidal neovascularization. Therapeutic approaches other than laser treatment could be attempted in these patients.
ISSN: 0721-832X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Occupational, Environmental and Insurance Medicine (-)
Research Group Ophthalmology
× corresponding author
# (joint) last author

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