Title: Optimal-control of the penicillin-g fed-batch fermentation - an analysis of a modified unstructured model
Authors: Van Impe, Jan ×
Nicolai, Bart
Vanrolleghem, P
Spriet, J
De Moor, Bart
Vandewalle, Joos #
Issue Date: 1992
Publisher: Gordon breach sci publ ltd
Series Title: Chemical engineering communications vol:117 pages:337-353
Abstract: This paper presents the application of optimal control theory in determining the optimal glucose feed rate profile for the penicillin G fed-batch fermentation, using a modified unstructured mathematical model based on balancing methods. This updated model allows for a smooth transition between maintenance and endogenous metabolism, while all variables take on physically acceptable values under all conditions.
ISSN: 0098-6445
Publication status: published
KU Leuven publication type: IT
Appears in Collections:ESAT - STADIUS, Stadius Centre for Dynamical Systems, Signal Processing and Data Analytics
Bio- & Chemical Systems Technology, Reactor Engineering and Safety Section
Division of Mechatronics, Biostatistics and Sensors (MeBioS)
× corresponding author
# (joint) last author

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