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Title: A chromosome 18 genetic linkage study in three large Belgian pedigrees with bipolar disorder
Authors: Claes, Stephan ×
Raeymaekers, P
Van den Broeck, M
Diependaele, S
De bruyn, A
Verheyen, G
Wils, V
Boogaerts, Andrea
Tanghe, A
Godderis, Jan
Van Broeckhoven, C
Cassiman, Jean-Jacques #
Issue Date: May-1997
Series Title: Journal of affective disorders. vol:43 issue:3 pages:195-205
Abstract: The contribution of genetic factors to the susceptibility for affective disorders has been firmly established. Recent reports found evidence for a susceptibility locus for affective disorders in 2 regions on chromosome 18. We describe 3 large Belgian pedigrees with multiple patients with affective disorders. Both chromosome 18 regions were investigated in the 3 families, using parametric and nonparametric segregation methods. In the pericentromeric region, all evidence was against a disease gene in our families. Also the data obtained for the distal part of 18q, argue against a genetic susceptibility factor in our sample.
ISSN: 0165-0327
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Human Mutations and Polymorphisms Section (-)
Research Group Psychiatry
Forensic Biomedical Sciences
× corresponding author
# (joint) last author

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