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Title: Auditory and visual event-related potentials in alcoholics: abnormalities of components and brain electrical field
Authors: Olbrich, HM
Maes, Hugo
Gann, H
Hagenbuch, F
Feige, B #
Issue Date: Oct-2000
Publisher: Dr dietrich steinkopff verlag
Series Title: European archives of psychiatry and clinical neuroscience vol:250 issue:5 pages:215-220
Abstract: Alterations of ERPs recorded over midline scalp sites have frequently been reported in alcoholics. To assess the P3 and other ERP components topographically auditory and visual ERPs were recorded from 33 scalp electrodes in abstinent alcoholics and healthy controls using an oddball paradigm. At the Ct electrode the alcoholics showed decreased visual N1 and increased auditory N2 amplitudes. Topographically, the negative centroids of the visual N1 and P3 and the auditory N2 differed between groups, and the positive centroid of the visual P3 was displaced toward the right hemisphere. While no valid diagnostic classification could be obtained by using the traditional ERP component P3 recorded from Pt, the combination of visual N1 and auditory N2 amplitudes at Ct with centroid parameters amounted to 51% explained variance and 92 % correct discrimination of alcoholics from controls. Abnormalities of N1 amplitude and P3 topography similar to the current findings in alcoholics have previously been described for schizophrenics.
URI: 
ISSN: 0940-1334
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Research Group Neurophysiology
Teacher Training, Faculty of Kinesiology and Rehabilitation Sciences
# (joint) last author

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