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Title: Cadherin-dependent cell-aggregation is affected by decapeptide derived from rat extracellular-superoxide dismutase
Authors: Willems, Jean ×
Bruyneel, E
Noe, V
Slegers, H
Zwijsen, An
Mege, Rm
Mareel, M #
Issue Date: Apr-1995
Publisher: Elsevier science bv
Series Title: FEBS Letters vol:363 issue:3 pages:289-292
Abstract: A synthetic HAV-containing decapeptide homologous to the amino acid sequence (44)R-Q(53) in rat extracellular superoxide dismutase B affects cadherin-dependent cell aggregation. Cell hues, some of them transfected, expressing different types of cadherins were tested using in vitro cell aggregation and cell dissociation assays, A concentration-dependent inhibition of aggregation by the EC-SOD-derived HAV-containing peptide was detected only in N-cadherin expressing cells, These results suggest the localisation and possible protective role of EC-SOD B for cells expressing N-cadherin.
ISSN: 0014-5793
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Faculty of Medicine, Campus Kulak Kortrijk
Molecular Biology (Celgen) (-)
Department of Human Genetics - miscellaneous
× corresponding author
# (joint) last author

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